Sponsor: National Institutes of Health, National Institute on Minority Health and Health Disparities (R01MD006198) PI: Geri Donenberg, Co-I: Erin Emerson, Project Director: Kelly McCabe
IMARA (Informed, Motivated, Aware, and Responsible about AIDS) is a culturally relevant, multi-level, integrated, family-based, HIV and mental health prevention program that simultaneously targets African American women and their daughters.
Sponsor: National Institutes of Health, National Institute on Minority Health and Health Disparities (R01MD010433) PI: Geri Donenberg, Co-I: Erin Emerson, Project Director: Erin McCarville
PHAT Life: Preventing HIV/AIDS Among Teens is an intervention designed to help youth on juvenile probation make healthy choices regarding sexual health and substance use. The intervention content provides youth with health knowledge and emotional management skills which help them make healthy decisions. The program is comprised of 8 sessions that are delivered over a 2-week period to small groups of youth.
We deliver the program in partnership with the Cook County Juvenile Probation Department at probation programming throughout the Chicagoland area.
Substance Use Programming for Person-Oriented Recovery Treatment (SUPPORT)
Sponsor: National Institute on Drug Abuse (R34DA041640) Multiple Principal Investigators: Brad Ray, PhD and Dennis Watson, PhD
There is a lack of evidence-based SUD treatment and services targeting returning inmates. Substance Use Programming for Person-Oriented Recovery Treatment (SUPPORT) is a community-driven, recovery-oriented approach to substance abuse care which has the potential to address this service gap. SUPPORT is modeled after Indiana’s Access to Recovery (ATR) program, which was closed due to lack of federal support despite positive improvements in clients’ recovery outcomes. SUPPORT builds on the limitations of ATR in that it will: focus specifically on a prison reentry population; be community-driven, rather than state administered; require direct service staff be certified peer recovery coaches; provide clients a full year of services instead of 6-months; and utilize an electronic data capture system, rather than paper surveys, to improve data-driven decision making. The ultimate goal of this project is the establishment of SUPPORT as an effective and scalable recovery-oriented system of care.
Planned Outreach, Intervention, Naloxone, and Treatment (POINT)
Sponsor: National Institute on Drug Abuse (R33DA045850) (R21DA045850) Principal Investigator: Dennis Watson, PhD
Despite significant need, substantial treatment and design barriers prevent many opioid users from accessing medication assisted treatment (MAT), the gold standard treatment for opioid use disorder (OUD). Planned Outreach, Intervention, Naloxone, and Treatment (POINT) is an emergency department (ED)-based outreach program for engaging opioid overdose survivors into MAT. It accomplishes this through use of recovery coaches (i.e., individuals with lived experience of recovery who are trained to assist those struggling with addiction) who assist patients to navigate barriers to MAT access after ED discharge. The primary goal of this project is the establishment of POINT as an effective and scalable intervention for engaging patients in MAT. This study employs a Hybrid Type 1 effectiveness-implementation design to take full advantage of current POINT expansion efforts currently happening in Indiana.
POINT was developed by Dr. Krista Brucker, Department of Emergency Medicine, Indiana University School of Medicine
Sponsor: National Institute on Drug Abuse (R34DA036001) (R36DA027770) Principal Investigator: Dennis Watson, PhD
Housing First is an evidenced-based approach to providing people with quick access to housing with services. Large national funders like the U.S. Department of Housing and Urban Development (HUD) and the Substance Abuse and Mental Health Services Administration (SAMHSA), and an increasing number of local funders are adopting this model as a best practice approach.
The Housing First Technical Assistance and Training (HFTAT) program was developed by the Midwest Harm Reduction Institute of Heartland’s Center for Systems Change to help organizations offer effective Housing First programs in their communities. HFTAT is a “blended implementation strategy”, employing face-to-face technical assistance and training, which includes a number of additional smaller strategies including the following: readiness and barrier assessment, identification and training of implementation leaders, implementation plan tailoring, building buy-in, and development of quality monitoring tools and systems.
UIC/AJCU Training Program in Advanced Research Methods and Translational Science
Sponsor: NIH, Fogarty International Center – HIV Research Training (D43TW010935) Principal Investigator: Judith Levy, MD
The “UIC/AJCU Training Program in Advanced Research Methods and Translational Science” is designed to build AIDS research capacity at Atma Jaya Catholic University (AJCU) in Jakarta, train a cadre of highly prepared Indonesian investigators to conduct innovative HIV/AIDS research using advanced research methods and translational science, and contribute to AJCU’s further development as a Center of Research Excellence for Indonesia. The program meets the NIH-identified overarching priority of providing the workforce research training required to conduct High Priority HIV/AIDS or HIV/AIDS-related research. In doing so, its focus on advanced research methods and translational science fits the needs of AJCU and its AIDS Research Center to build institutional and investigator capacity in using advanced methodological tools to address the country’s need for innovative research to guide its HIV/AIDS programming and social policy and the long-term benefits of the program lie in its impact on improving HIV prevention, treatment, and services for Indonesia.
IMPAACT – Evaluating a Group-Based Intervention to Improve Mental Health and ART Adherence Among Youth Living with HIV in Low Resource Settings
Sponsor: International Maternal Pediatric And Adolescent Clinical Trials network (IMPAACT) Co-chairs: Dorothy Dow, MD and Geri Donenberg, PhD
This study will evaluate whether an Indigenous Leader Outreach Model (ILOM) of trauma-informed cognitive behavioral therapy (TI-CBT) is associated with improved mental health outcomes and ART adherence among 15-19 year-olds youth living with HIV and mental health distress. It is a multi-site, two-arm, individually randomized controlled trial preceded by Focus Groups and Pilot Testing to adapt the intervention to the local context.
Step Up Test Up
Sponsor: National Institutes of Health, National Institute on Drug Abuse (R01DA041071) Principal Investigators: Rob Garofalo, MD and Niranjin Karnik, MD UIC PI: Geri Donenberg
In partnership with Lurie Children’s Hospital and principle investigator Rob Garafalo, the Step Up Test Up study is a randomized controlled trial that seeks to test whether an electronic brief intervention will reduce alcohol and other substance use among youth aged 16-25. Participants are recruited from HIV testing locations throughout the city of Chicago and include men who have sex with men as well as transgender women and men.
Kigali Imbereheza Project (KIP)
Sponsor: National Institutes of Health, Eunice Kennedy Shriver Human Development (R01HD074977) Principal Investigators: Geri Donenberg, PhD, Mardge Cohen, MD and Sabin Nsanzimana, MD
The Kigali Imbereheza Project is a randomized controlled trial based in Kigali, Rwanda that seeks to test an adherence-enhanced, developmentally appropriate, culturally adapted trauma informed cognitive behavioral intervention (TI-CBTe) on antiretroviral therapy adherence among HIV+ Rwandan youth. KIP is a collaboration with Mardge Cohen, MD, Medical Director of the WE-ACTx clinic in Kigali, Rwanda and a faculty member at Hektoen Institute for Medical Research, LLC /Cook County Health and Hospitals System (CCHHS); and Sabin Nsanzimana, MD, Head of HIV AIDS, STI, Blood Borne Infections at the Rwanda Biomedical Center.