Xiandong Zhu, MD

Research Associate Professor

Department of Emergency Medicine

About

Dr. Xiangdong Zhu is a physician-scientist whose research focuses on the cellular and molecular mechanisms of allergic inflammation, with particular emphasis on eosinophil activation, adhesion, and trafficking in asthma and airway disease. His work investigates intracellular signaling pathways that regulate immune cell behavior in the pulmonary environment, with the goal of identifying new therapeutic targets to improve outcomes for patients with asthma and related inflammatory airway disorders.

Dr. Zhu has held research appointments in pulmonary and critical care medicine and has contributed to multi-institutional collaborative programs supported by national research agencies and industry partners. His work bridges laboratory discovery with clinically relevant questions in immunology and inflammation.

Selected Grants

American Lung Association, Role of cytosolic phospholipase A2 in eosinophil adhesion, Principal Investigator

National Heart, Lung, and Blood Institute (NHLBI), Mechanisms of Asthma – Project II, Co-Investigator

National Institute of Allergy and Infectious Diseases (NIAID), Mechanism of eosinophil adhesion, Principal Investigator

GlaxoSmithKline, Regulation of β2 integrin–mediated eosinophil adhesion with salmeterol and fluticasone, Principal Investigator

National Heart, Lung, and Blood Institute (NHLBI), Regulation of eosinophil trafficking by Pyk2, Principal Investigator

GlaxoSmithKline, CAPSTONE Project: Airway studies on neutrophils and eosinophils, Co-Investigator

Publication Aggregators

Publication Listing

Education

Education
M.D. — Xinxiang Medical College, Xinxiang, China
M.S., Radiation Oncology — Xi’an Medical University, Xi’an, China

Postgraduate Training
Postdoctoral Research Fellowship, Pulmonary and Critical Care Medicine — University of Chicago

Research Currently in Progress

Research Interests