RECENT GRANTS & AWARDS

Faculty PI and Co-Investigators (Active)

Oana Danciu, MD
(PI) “A Window-of-opportunity Trial of anti-VEGFR Therapy Combined with Immune Checkpoint Blockade in Early-stage, Triple-negative Breast Cancer”

Lawrence Feldman, MD
(PI) (UICMC): Coleman 4R Patient Care Sequences for Cancer and Supportive Care

Saverio Gentile, MD, PhD
(PI) DOD “Therapeutic benefit of potassium channels activators in triple-negative breast cancer.”

Kent Hoskins, MD
(Co-I) R01 “Repression function of FoxM1 in tumor metastasis”
(PI) “A Window-of-opportunity Trial of anti-VEGFR Therapy Combined with Immune Checkpoint Blockade in Early-stage, Triple-negative Breast Cancer”
(Co-I) “The influence of Duffy Antigen Receptor for Chemokines (DARC) on immune-checkpoint inhibition (ICI) in African American patients with triple negative breast cancer”
(PI) “Therapeutic benefit of potassium channel activators in triple-negative breast cancer”

V.K. Gadi, MD, PhD
(PI) “MammaPrint, BluePrint, and Full-genome Data Linked with Clinical Data to Evaluate New Gene EXpression Profiles: An Adaptable Registry (FLEX Registry)”
(PI) “Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer”
(PI) “The CompassHER2 Trials (Comprehensive Use of Pathologic Response Assessment to Optimize Therapy in HER2-Positive Breast Cancer) CompassHER2 Residual Disease (RD), a Double-Blinded, Phase III Randomized Trial of T-DM1 Compared with T-DM1 and Tucatinib”
(PI) “(CompassHER2-pCR): Preoperative THP and Postoperative HP in Patients Who Achieve a Pathologic Complete Response”
(PI) “A First-in-human, Phase 1 Study to Evaluate the Safety of TTX-080, an HLA-G Antagonist, in Subjects with Advanced Solid Tumors”
(Co-I) “Developing an Online Resource to Study MicroRNA Dysregulation in Cancer”
(PI) “A Phase 2 Study of Autologous Tumor Infiltrating Lymphocytes (LN-145) in Patients with Pretreated Metastatic Triple Negative Breast Cancer”

Victor Gordeuk, MD
(PI) “Improving Sickle Cell Care in Adolescents & Adults in Chicago (ISAAC)”
(Co-I) R01 “Vascular-targeted Genomic and Genetic Strategies for Acute Chest Syndrome”
(Co-I) “Africa Kidney Disease Network”  

Nadim Mahmud, MD, PhD
(PI) R01 “ADAMTS13 Culture Red Blood Cells to Treat TTP”
(Co-I) R01 “Improving the interaction of hematopoietic stem cells with perivascular niche to promote engraftment.”
(Co-I) DOD “Phase I II Multicenter Randomized Controlled Clinical Trial of Mesenchymal Stem Cell Therapy for Severe Ocular Surface Chemical Injuries”
(PI) NIH “Development of HDAC8 inhibitors for treatment of AML Agency:”
(Co-I) NIH “Role of DDX41 in HSC development and leukemia”
(Co-I) DOD “Novel Immunomodulatory Approach of Tailored Stem Cell Based Therapy for Tolerance Induction in Vascularized C”
(Co-I) DOD “Biologically inspired manufacturing of therapeutic extracellular vesicles to treat lung injury”

Santosh Saraf, MD
R01 (PI) “Pathways of Cell-free hemoglobin in Sickle Cell Nephropathy”
R01 (MPI) “Predicting Progression of Chronic Kidney Disease in Sickle Cell Anemia Using Machine Learning Models”
R01 (CoI) “Improving Scientific Rigor of Clinical Endpoints for Sickle Cell Anemia”
R01 (CoI) “Molecular and Cellular Pathogenesis of Kidney Disease in Sickle Cell Disorders”
U54 (Project Co-Leader) H3 Africa: Sickle Cell Disease Nephropathy
Global Blood Therapeutics (IIT PI) “A pilot study of Voxelotor for Sickle Cell anemia Patients at Highest Risk for Progression of Kidney Disease”
Novartis (IIT PI) “Clinical, Laboratory, and Genetic Predictors for Sickle cell Nephropathy”

INSTRUCTIONS: In order to add a sidebar anchor:

  1. Duplicate the existing item, listed as a 1/6 text field. (Or create a 1/6 column and add a text field, modify the class so it’s exactly “additionalAnchor”).
  2. Modify the text field inside the 1/6 column. Inside there, modify the HYPERLINK so that it would go to a corresponding section with a “#” in front of it. (Example, we have a “chief” section on the page, then it would make sense to have the hyperlink go to “#chief”)
  3. Then change the hyperlink TEXT to a appropriate label.
  4. IMPORTANT: If not done already, go into that CONTAINER that corresponds to your anchor (i.e. Meet The Chiefs), and add an ID matching the anchor’s HYPERLINK WITHOUT the “#”, i.e. “chief”.
  5. (If using side bar widget box, then there’s a saved copy of a widget box COLUMN, grab it in the column library, it should 1/6 of a length of a column.)

NOTE: Order added to the sidebar is from last to first.