Clinical and Pharmaceutical Studies Completed Projects
Completed Projects Heading link
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Research by PI Boucher-Berry, Claudia
Sponsor
Eli Lilly & Co
Title
A Randomized, Double-Blinded Study with an Open-Label Extension Comparing the Effect of Once-Weekly Dulaglutide with Placebo in Pediatric Patients with Type 2 Diabetes Mellitus (AWARD-PEDS) H9X-MC-GBG
Description
Clinical trial of a novel therapy for children with Diabetes Type2.
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Research by PI Boucher-Berry, Claudia
Sponsor
Lurie Children’s (Prime sponsor: NIH)
Title
Effectiveness of an e-health intervention
Description
UIC is a site for this trial, led by Lurie Children’s Hospital, which aims to determine effectiveness of the use of technology for care support in minority children with diabetes.
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Research by PI Czech, Kimberly
Sponsor
North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS)
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Research by Harsha Vardhan, Sinhuja
Title
Measurement of Negative Inspiratory Flow (NIF) in Children Aged 4-8 Years During an Acute Asthma Exacerbation to Predict Effectiveness of Dry Powder Inhaler – A Pilot Study
Description
There are several types of Dry Powder Inhaler (DPI) devices currently on the market used for delivering glucocorticoids, beta-agonists, or combination medication (i.e. diskus, twisthaler/turbuhaler, respiClick). Each type of DPI has a different intrinsic resistance to airflow that determines how much inspiratory flow needs to be created in the device to release the correct amount of drug. Children who cannot achieve the recommended/optimal negative inspiratory flow (NIF) through their prescribed DPI may not obtain the maximum benefit from their medication. In this study, we will evaluate the use of DPI use in children during an acute asthma exacerbation, when NIF is inherently reduced. We hypothesize that the use of DPIs in children aged 4<8 during an asthma exacerbation has limited benefit, as children are unable to generate the needed NIF.
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Research by Kirshnan, Sonia
Funder
Children’s Hospital of Philadelphia (Prime sponsor: NIH)
Title
Chronic Kidney Disease in Children
Abstract
Chronic kidney disease (CKD) is a life-long condition that often results in substantial morbidity and premature death due to complications from a progressive decrease in kidney function. The early detection of, and initiation of therapy for, CKD is key to delaying or preventing progression to end-stage renal disease (ESRD). The CKiD (Chronic Kidney Disease in Children) study is a prospective cohort study of children with CKD that investigates risk factors and outcomes of the disease.
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Research by Srinivasan, Nishant
Title
A Retrospective Analysis of Acute Kidney Injury in VLBW Infants
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Research by Srinivasan, Nishant
Funder
Univ of WA (Primary sponsor: NIH NINDS)
Title
Preterm Epo Neuroprotection Trial (PENUT Trial) CCC
Description
The aim of this NINDS funded trial is to assess whether high dose Epo will improve survival without neurodevelopmental impairment (NDI) in infants born between 24 and 28 weeks of gestation (term is 40 weeks). 940 infants will be enrolled at 16 centers across the U.S. Subjects will be assessed at 2 years of age to see whether Epo treatment will improve neurodevelopmental outcomes.
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Research by Srinivasan, Nishant
Title
Blood Pressure Trends in Very Low-Birth Weight Infants and Contributors of Neonatal Hypertension
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Research by Srinivasan, Nishant
Title
Infant Social-Emotional Development, Maternal Mental Well-being, Sense of Parenting Competency, and Parent-Infant Bonding in NICU Families During the COVID-19 Era
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Research by Srinivasan, Nishant
Title
Effect of Direct Parental Involvement on Achievement of Independent Oral Feeding in Late Preterm Infants
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Research by Srinivasan, Nishant
Title
Contributors of Renal Dysfunction and Neonatal Hypertension in Very Low-Birth Weight Infants
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Research by Srinivasan, Nishant
Title
Development, Validation and Implementation of Neonatal Pericardiocentesis and Thoracentesis Training Using a Surgical Simulation Assistant Platform