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ICOD3 Projects

Learn more about Illinois Center for Drug and Diagnostic Development projects, both pre-clinical and clinical.

DOVS-Mc100: Contrast Sensitivity Eye Chart Heading link

DOVS-Aa100: Wound Healing Peptides Heading link

DOVS-Dj100: (MSC) Exosomes Heading link

DOVS-Dj200: Topical MEK Inhibitor Heading link

DOVS-Kz100: Diabetic Retinopathy Biomarker Heading link

DOVS-Sh100: Anti-Heparin Sulfate Peptides G1 and G2 Heading link

DOVS-Sh200: DECON Heading link

DOVS-Sh300: PBA Heading link

DOVS-Ya100: KAI Heading link

Clinical Projects Heading link

DOVS-Ja100: Antibody Based Eye Drops is a project focused on developing antibody-based eye drops that can be used for treatment of ocular surface diseases.

DOVS-Ja200: DNase Eye Drops is a project focused on developing DNase eye drops that can be used for treatment of ocular surface diseases.

Possible indications

Ocular surface diseases

Prevalence/target population

Dry eye syndrome affects between 4 to more than 20% of the population and becomes more common with age. A variety of patient and environmental factors can increase the risk of symptomatic and severe inflammatory manifestations of dry eye disease.1

Status

Both projects are TRL 6. Phase 1 clinical trials completed, data support proceeding to Phase 2 clinical trials, IND application prepared and submitted.