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Photo of Gordeuk, Victor

Victor Gordeuk, MD

Professor of Medicine

Department of Medicine, Division of Hematology and Oncology


Area of Interest
Sickle Cell Disease
Congenital Erythrocytosis
Iron Metabolism

1988-1989 Senior International Fellowship, Fogarty Center, National Institutes of Health
1986-1987 Cooley’s Anemia Foundation Research Fellowship 1974 Reader’s Digest International Fellowship

Recent Publications
Kroner BL, Hankins JS, Pugh N, Kutlar A, King AA, Shah NR, Kanter J, Glassberg J, Treadwell M, Gordeuk VR; Sickle Cell Disease Implementation Consortium. Pregnancy outcomes with hydroxyurea use in women with sickle cell disease. Am J Hematol. 2022 May;97(5):603-612. PMID: 35142007.

Njoku F, Zhang X, Shah BN, Machado RF, Han J, Saraf SL, Gordeuk VR. Biomarkers of clinical severity in treated and untreated sickle cell disease: a comparison by genotypes of a single center cohort and African Americans in the NHANES study. Br J Haematol. 2021 Aug;194(4):767-778. PMID: 34268729.

Gordeuk VR, Shah BN, Zhang X, Thuma PE, Zulu S, Moono R, Reading NS, Song J, Zhang Y, Nouraie M, Campbell A, Minniti CP, Rana SR, Darbari DS, Kato GJ, Niu M, Castro OL, Machado R, Gladwin MT, Prchal JT. CYB5R3c.350C>G and G6PD A Alleles Modify Severity of Anemia in Malaria and Sickle Cell Disease. Am J Hematol. 2020 Nov;95(11):1269-1279. PMID: 32697331

Zhang X, Song J, Shah BN, Nekhai S, Miasnikova G, Sergueeva A, Prchal JT, Gordeuk VR. Peripheral blood mononuclear cells show prominent gene expression by erythroid progenitors in diseases characterized by heightened erythropoiesis. Br J Haematol. 2020 Jul;190(1):e42-e45. PMID: 32399971.

Nouraie M, Darbari DS, Rana S, Minniti CP, Castro OL, Luchtman-Jones L, Sable C, Dham N, Kato GJ, Gladwin MT, Ensing G, Arteta M, Campbell A, Taylor JG 6th, Nekhai S, Gordeuk VR. Tricuspid regurgitation velocity and other biomarkers of mortality in children, adolescents and young adults with sickle cell disease in the United States: The PUSH study. Am J Hematol. 2020 Jul;95(7):766-774. PMID: 32243618.

Shah BN, Hassan TO, Zhang X, McClain DA, Gordeuk VR. Increased iron stores influence glucose metabolism in sickle cell anaemia. Br J Haematol. 2020 May;189(4):e184-e187.  PubMed PMID: 32232834.

Gordeuk VR, Miasnikova GY, Sergueeva AI, Lorenzo FR, Zhang X, Song J, Stockton DW, Prchal JT. Thrombotic risk in congenital erythrocytosis due to up-regulated hypoxia sensing is not associated with elevated hematocrit. Haematologica. 2020 Mar;105 (3):e87-e90 PubMed PMID: 31289208.

Zhang X, Shah BN, Zhang W, Saraf SL, Nouraie M, Nekhai S, Machado RF, Gladwin MT, Gordeuk VR. S100B has pleiotropic effects on vaso-occlusive manifestations in sickle cell disease. Am J Hematol. 2020 Mar;95(3):E62-E65. PMID: 31805207.

Vichinsky E, Hoppe CC, Ataga KI, Ware RE, Nduba V, El-Beshlawy A, Hassab H, Achebe MM, Alkindi S, Brown RC, Diuguid DL, Telfer P, Tsitsikas DA, Elghandour A, Gordeuk VR, Kanter J, Abboud MR, Lehrer-Graiwer J, Tonda M, Intondi A, Tong B, Howard J; HOPE Trial Investigators. A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease. N Engl J Med. 2019 Aug 8;381(6):509-519. PubMed PMID: 31199090.

Title of grant: “Improving Sickle cell care in Adolescents & Adults in Chicago (ISAAC)”
Funding agency: NIH/NHLBI
UIC Corresponding PI: Gordeuk

Title of grant: “A Phase IIB Randomized Double-Blind Placebo Controlled Multi-Center Study to Assess the Safety, Tolerability and Efficacy of Riociguat in Patients with SCD (STERIO-SCD)”
Funding Agency: University of Pittsburgh/Bayer
UIC Site PI: Gordeuk

Title of grant: “Vascular-targeted Genomic and Genetic Strategies for Acute Chest Syndrome”
Funding agency: National Institutes of Health
UIC Site PI: Gordeuk

Title of grant: “A Phase 1/2 randomized, double-blind, placebo-controlled, multicenter, ascending dose, safety and PK/PD study of SHP655 (rADAMTS13) in sickle cell disease at baseline health and during acute vaso-occlusive crisis”
Funding agency: Baxalta/Shire
UIC Site PI: Gordeuk

Title of grant: “Sickle Cell Disease and CardiovAscular Risk – Red Cell Exchange Trial (SCD-CARRE)”
Funding agency: NHLBI/University of Pittsburgh
UIC Site PIs: Gordeuk and Campbell-Lee

Title of grant: “Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell via Mobile Applications (CaRISMA)”
Funding agency: PCORI/University of Pittsburgh
UIC Site PI: Gordeuk


Medical School: University of Pittsburgh School of Medicine
Residency: York Hospital
Fellowship: Case Western Reserve University