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Joanne Tobacman , MD

Associate Professor of Clinical Medicine Staff Physician, Jesse Brown VAMC
Work University of Illinois at Chicago (MC 718) 440 Clinical Sciences North 840 S Wood St, Chicago, IL 60612 Office Phone: 312-569-7826 Publications Website: Publications
Photo of Joanne Tobacman , MD

Biographical Info

In recent years, Dr. Tobacman’s work has focused on the harmful effects of the common food additive carrageenan. Carrageenan resembles the naturally occurring sulfated glycosaminoglycans, but interferes with their normal functions. Her team has shown how carrageenan contributes to human diseases, including inflammatory bowel disease and diabetes, due to its stimulation of inflammation. Examination of the role of sulfatase enzymes, particularly the chondroitin sulfatases, has focused on their role in malignancy and in mediation of cell signaling through effects on chondroitin sulfation. They have also identified decline in arylsulfatase B (N-acetylgalactosamine-4-sulfatase) in cystic fibrosis.

Education History

Medical School: Case Western Reserve University
Residency: University Hospitals of Cleveland and Cleveland VA Hospital
Fellowship: National Cancer Institute, Medicine Branch and Environmental Epidemiology Branch

Research Projects

  1. Impact of the no-carrageenan diet on glucose tolerance and insulin resistance in prediabetes.
  2. Role of chondroitin sulfatases in prostate cancer.
  3. Decline of arylsulfatase B (N-acetylgalactosamine-4-sulfatase) leads to increase in PD-L1 in melanoma.

Curriculum Vitae

Categories: DOM – AIM – Faculty
Updated 9 months ago.

Current Fellows

Joanne Tobacman , MD

Associate Professor of Clinical Medicine Staff Physician, Jesse Brown VAMC
Work University of Illinois at Chicago (MC 718) 440 Clinical Sciences North 840 S Wood St, Chicago, IL 60612 Office Phone: 312-569-7826 Publications Website: Publications
Photo of Joanne Tobacman , MD

Biographical Info

In recent years, Dr. Tobacman’s work has focused on the harmful effects of the common food additive carrageenan. Carrageenan resembles the naturally occurring sulfated glycosaminoglycans, but interferes with their normal functions. Her team has shown how carrageenan contributes to human diseases, including inflammatory bowel disease and diabetes, due to its stimulation of inflammation. Examination of the role of sulfatase enzymes, particularly the chondroitin sulfatases, has focused on their role in malignancy and in mediation of cell signaling through effects on chondroitin sulfation. They have also identified decline in arylsulfatase B (N-acetylgalactosamine-4-sulfatase) in cystic fibrosis.

Education History

Medical School: Case Western Reserve University
Residency: University Hospitals of Cleveland and Cleveland VA Hospital
Fellowship: National Cancer Institute, Medicine Branch and Environmental Epidemiology Branch

Research Projects

  1. Impact of the no-carrageenan diet on glucose tolerance and insulin resistance in prediabetes.
  2. Role of chondroitin sulfatases in prostate cancer.
  3. Decline of arylsulfatase B (N-acetylgalactosamine-4-sulfatase) leads to increase in PD-L1 in melanoma.

Curriculum Vitae

Categories: DOM – AIM – Faculty
Updated 9 months ago.

Staff

Joanne Tobacman , MD

Associate Professor of Clinical Medicine Staff Physician, Jesse Brown VAMC
Work University of Illinois at Chicago (MC 718) 440 Clinical Sciences North 840 S Wood St, Chicago, IL 60612 Office Phone: 312-569-7826 Publications Website: Publications
Photo of Joanne Tobacman , MD

Biographical Info

In recent years, Dr. Tobacman’s work has focused on the harmful effects of the common food additive carrageenan. Carrageenan resembles the naturally occurring sulfated glycosaminoglycans, but interferes with their normal functions. Her team has shown how carrageenan contributes to human diseases, including inflammatory bowel disease and diabetes, due to its stimulation of inflammation. Examination of the role of sulfatase enzymes, particularly the chondroitin sulfatases, has focused on their role in malignancy and in mediation of cell signaling through effects on chondroitin sulfation. They have also identified decline in arylsulfatase B (N-acetylgalactosamine-4-sulfatase) in cystic fibrosis.

Education History

Medical School: Case Western Reserve University
Residency: University Hospitals of Cleveland and Cleveland VA Hospital
Fellowship: National Cancer Institute, Medicine Branch and Environmental Epidemiology Branch

Research Projects

  1. Impact of the no-carrageenan diet on glucose tolerance and insulin resistance in prediabetes.
  2. Role of chondroitin sulfatases in prostate cancer.
  3. Decline of arylsulfatase B (N-acetylgalactosamine-4-sulfatase) leads to increase in PD-L1 in melanoma.

Curriculum Vitae

Categories: DOM – AIM – Faculty
Updated 9 months ago.

Affiliated Faculty

Joanne Tobacman , MD

Associate Professor of Clinical Medicine Staff Physician, Jesse Brown VAMC
Work University of Illinois at Chicago (MC 718) 440 Clinical Sciences North 840 S Wood St, Chicago, IL 60612 Office Phone: 312-569-7826 Publications Website: Publications
Photo of Joanne Tobacman , MD

Biographical Info

In recent years, Dr. Tobacman’s work has focused on the harmful effects of the common food additive carrageenan. Carrageenan resembles the naturally occurring sulfated glycosaminoglycans, but interferes with their normal functions. Her team has shown how carrageenan contributes to human diseases, including inflammatory bowel disease and diabetes, due to its stimulation of inflammation. Examination of the role of sulfatase enzymes, particularly the chondroitin sulfatases, has focused on their role in malignancy and in mediation of cell signaling through effects on chondroitin sulfation. They have also identified decline in arylsulfatase B (N-acetylgalactosamine-4-sulfatase) in cystic fibrosis.

Education History

Medical School: Case Western Reserve University
Residency: University Hospitals of Cleveland and Cleveland VA Hospital
Fellowship: National Cancer Institute, Medicine Branch and Environmental Epidemiology Branch

Research Projects

  1. Impact of the no-carrageenan diet on glucose tolerance and insulin resistance in prediabetes.
  2. Role of chondroitin sulfatases in prostate cancer.
  3. Decline of arylsulfatase B (N-acetylgalactosamine-4-sulfatase) leads to increase in PD-L1 in melanoma.

Curriculum Vitae

Categories: DOM – AIM – Faculty
Updated 9 months ago.