Brain Tumor Center at UIC

Clinical Trials & Research Initiatives

The UIC Brain Tumor Center supports a number research initiatives, participates in cutting clinical trials, and conducts original research. Read more about the brain tumor research that is happening at UIC.

 

Clinical Trials:

Standard of care treatments exist for every tumor type, but options can be limited. For this reason, clinical trials are an essential component of care. To learn more about brain tumor clinical trials offered at the University of Illinois, call Jean Arzbaecher at (312)-996-3369 or send an email to: jeana@uic.edu or review these links:

Current Trials Open to Accrual Brain Tumors As of 6/1/2014
Clinical trials at NIH: http://clinicaltrials.gov/

 

Research Publications:

 

  1. Friedman, H.S., Prados, M.D., Wen, P.Y., Mikkelsen, T., Schiff, D., Abrey, L.E., Yung, W.K., Paleologos, N., Nicholas, M.K., Jensen, R., Vredenburgh, J., Huang, J., Zheng, M., & Cloughesy, T. (2009).Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma.Journal of Clinical Oncology, 27(28), 4733-40.
  2. Wefel, J.S., Cloughesy, T., Zazzali, J.L., Zheng, M., Prados, M., Wen, P.Y., Mikkelsen, T., Schiff, D., Abrey, L.E., Yung, W.K., Paleologos, N., Nicholas, M.K., Jensen, R., Vredenburgh, J., Das, A., & Friedman, H.S. (2011).Neurocognitive function in patients with recurrent glioblastoma treated with bevacizumab.Neuro-Oncology, 13(6), 60-8
  3. O’Donnell, P.H., Undevia, S.D., Stadler, W.M., Karrison, T.M., Nicholas, M.K., Janisch, L., & Ratain, M.J. (2012).A phase I study of continuous infusion cilengitide in patients with solid tumors.Investigation of New Drugs, 30(2), 604-10
  4. Tye, K., Engelhard, H.H., Slavin, K.V., Nicholas, M.K., Chmura, S.J., Kwok, Y., Ho, D.S., Weichselbaum, R.R., & Koshy, M. (2014).An analysis of radiation necrosis of the central nervous system treated with bevacizumab.Journal of Neuro-Oncology, 117(2), 321-7
  5. Liang, Y., Diehn, M., Bollen, A.W., Aldape, K.D., Nicholas, M.K., Lamborn, K.R., Berger, M.S., Botstein, D., Brown, P.O., & Israel, M.A. (2005).Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme.Proceedings of the National Academy of Science, 102(16), 5814-5819, 2005.
  6. Nicholas MK, Lukas RV, Chmura S, Yamini B, Lesniak M, Pytel P.Molecular heterogeneity in glioblastoma: opportunities and challenges.Semin Oncol. 2011 Apr;38(2):243-53.