Lawrence S. Chan, MD
Dr. Orville J. Stone Professor of Dermatology James Lovell Federal Health Care Center (FHCC)
Biographical Info
Medical School: University of Pennsylvania
Internship: Medicine, Cooper Hospital/University Medical Center
Residency: Dermatology, University of Michigan
Fellowship: Immunodermatology, University of Michigan
Board Certifications: American Board of Dermatology, Dermatological Immunology
Clinical Interests: Immunodermatology, autoimmune bullous diseases, atopic dermatitis
Research Interests: Animal models of autoimmune bullous diseases of the skin, atopic dermatitis, and alopecia areata
Office Location: 1801 W. Taylor Street, Suite 3E, Chicago, IL 60612
To make an appointment: (312) 413-7783 or (312) 996-8666
Jump To: Books | Research Articles | Clinical Articles
Books
1.) Chan LS. Blistering Skin Diseases. Manson Publishing-American Society of Microbiology Press, 2009 (Link)
2.) Chan LS. Ed. Animal Models of Human Inflammatory Skin Diseases. CRC Press-Informa Health Care, 2003 (Link)
Research Articles
I. Atopic Dermatitis Research:
Bao L, Alexander JB, Shi VY, Mohan GC, Chan LS.
Immunology. 2014 Dec;143(4):601-8. doi: 10.1111/imm.12339.
- PMID:
- 24943510
Reichle ME, Chen L, Lin SX, Chan LS.
J Invest Dermatol. 2011 Mar;131(3):791-4. Epub 2010 Dec 30. No abstract available.
- PMID: 21191418 [PubMed – indexed for MEDLINE]
Chen L, Lin SX, Amin S, Overbergh L, Maggiolino G, Chan LS.
Immunol Cell Biol. 2010 Mar-Apr;88(3):334-42. Epub 2010 Jan 12.
- PMID: 20065994 [PubMed – indexed for MEDLINE]
Peterson JD, Chan LS.
Ther Clin Risk Manag. 2009 Feb;5(1):1-7. Epub 2009 Mar 26.
- PMID: 19436603 [PubMed]
Chen L, Overbergh L, Mathieu C, Chan LS.
Clin Exp Allergy. 2008 Aug;38(8):1367-80. Epub 2008 Apr 13.
- PMID: 18489026 [PubMed – indexed for MEDLINE]
Microcirculation. 2008 Jan;15(1):49-64.
PMID: 17952801 [PubMed – indexed for MEDLINE]
Int Immunol. 2006 Aug;18(8):1233-42. Epub 2006 May 30.
PMID: 16735375 [PubMed – indexed for MEDLINE]
Related Articles Free article at journal site
Clin Exp Immunol. 2005 Oct;142(1):21-30.
PMID: 16178852 [PubMed – indexed for MEDLINE]
Microcirculation. 2005 Sep;12(6):455-76.
PMID: 16147464 [PubMed – indexed for MEDLINE]
Clin Exp Immunol. 2005 Feb;139(2):189-201.
PMID: 15654817 [PubMed – indexed for MEDLINE]
Early up-regulation of Th2 cytokines and late surge of Th1 cytokines in an atopic dermatitis model.
Clin Exp Immunol. 2004 Dec;138(3):375-87.
PMID: 15544612 [PubMed – indexed for MEDLINE]
J Invest Dermatol. 2001 Oct;117(4):977-83.
PMID: 11676841 [PubMed – indexed for MEDLINE]
Related Articles Free article at journal site
II. Autoimmune and Inflammatory Disease Research:
Autoimmunity to type VII collagen in SKH1 mice is independent of regulatory T cells.
Clin Exp Immunol. 2006 Aug;145(2):322-31.
PMID: 16879253 [PubMed – indexed for MEDLINE]
Related Articles Free article in PMC | at journal site
Vet Dermatol. 2004 Jun;15(3):146-51.
PMID: 15214950 [PubMed – indexed for MEDLINE]
J Invest Dermatol. 2003 Nov;121(5):1021-8.
PMID: 14708601 [PubMed – indexed for MEDLINE]
Related Articles Free article at journal site
Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa.
Nat Genet. 2002 Dec;32(4):670-5. Epub 2002 Nov 11.
PMID: 12426566 [PubMed – indexed for MEDLINE]
Clin Exp Immunol. 2002 Mar;127(3):470-8.
PMID: 11966763 [PubMed – indexed for MEDLINE]
Related Articles Free article in PMC | at journal site
J Autoimmun. 2001 Jun;16(4):411-21. Erratum in: J Autoimmun 2001 Sep;17(2):173.
PMID: 11437489 [PubMed – indexed for MEDLINE]
Immunol Lett. 2001 Jun 1;77(2):105-11.
PMID: 11377704 [PubMed – indexed for MEDLINE]
J Clin Immunol. 2000 Nov;20(6):416-23.
PMID: 11202231 [PubMed – indexed for MEDLINE]
Vet Immunol Immunopathol. 2000 Jan 31;73(1):45-52.
PMID: 10678397 [PubMed – indexed for MEDLINE]
Clin Exp Immunol. 2000 Jan;119(1):217-24.
PMID: 10606986 [PubMed – indexed for MEDLINE]
Related Articles Free article in PMC | at journal site
Biochim Biophys Acta. 2000 Jan 3;1500(1):97-107.
PMID: 10564722 [PubMed – indexed for MEDLINE]
J Dermatol Sci. 1999 Nov;21(3):157-64.
PMID: 10527376 [PubMed – indexed for MEDLINE]
Vet Pathol. 1999 Jul;36(4):328-35.
PMID: 10421100 [PubMed – indexed for MEDLINE]
Related Articles Free article at journal site
Biochim Biophys Acta. 1998 Oct 22;1408(1):25-34.
PMID: 9784596 [PubMed – indexed for MEDLINE]
Laminin-6 and laminin-5 are recognized by autoantibodies in a subset of cicatricial pemphigoid.
J Invest Dermatol. 1997 Jun;108(6):848-53.
PMID: 9182809 [PubMed – indexed for MEDLINE]
Am J Pathol. 1997 Jun;150(6):1901-7.
PMID: 9176383 [PubMed – indexed for MEDLINE]
Related Articles Free article in PMC
Am J Pathol. 1997 Feb;150(2):675-83.
PMID: 9033280 [PubMed – indexed for MEDLINE]
Related Articles Free article in PMC
J Invest Dermatol. 1997 Feb;108(2):129-32.
PMID: 9008223 [PubMed – indexed for MEDLINE]
J Invest Dermatol. 1997 Jan;108(1):68-72.
PMID: 8980290 [PubMed – indexed for MEDLINE]
J Invest Dermatol. 1996 Aug;107(2):209-14.
PMID: 8757764 [PubMed – indexed for MEDLINE]
J Invest Dermatol. 1995 Jul;105(1):75-9.
PMID: 7615980 [PubMed – indexed for MEDLINE]
Vet Pathol. 1995 Jul;32(4):387-93.
PMID: 7483213 [PubMed – indexed for MEDLINE]
Clinical Articles
Dr. Chan’s clinical articles are depicted below, starting from the most recent papers:
An unusual clinical presentation of pemphigus herpetiformis with marked response to dapsone.
Montgomery JR, Chan LS.
J Am Acad Dermatol. 2011 Aug;65(2):436-8. No abstract available.
- PMID: 21763574[PubMed – indexed for MEDLINE]
Chan LS.
Arch Dermatol. 2011 Mar;147(3):291-2. No abstract available.
- PMID: 21422335[PubMed – indexed for MEDLINE]
Cutaneous adverse drug reactions in a hospital-based Chinese population.
Huang HY, Luo XQ, Chan LS, Cao ZH, Sun XF, Xu JH.
Clin Exp Dermatol. 2011 Mar;36(2):135-41. doi: 10.1111/j.1365-2230.2010.03922.x. Epub 2010 Aug 25.
- PMID: 20738322 [PubMed – indexed for MEDLINE]
Peterson JD, Chan LS.
Ther Clin Risk Manag. 2009 Feb;5(1):1-7. Epub 2009 Mar 26.
- PMID: 19436603 [PubMed]
Peterson JD, Worobec SM, Chan LS.
J Cutan Med Surg. 2007 Sep-Oct;11(5):179-84.
Linear IgA bullous dermatosis responsive to trimethoprim-sulfamethoxazole.
Peterson JD, Chan LS.
Clin Exp Dermatol. 2007 Nov;32(6):756-8. Epub 2007 Sep 14. No abstract available.
Extensive basal cell carcinoma with probable bone metastasis.
Rodriguez C, Barriuso V, Chan LS.
Cutis. 2007 Jul;80(1):60-6. Review.
Peterson JD, Chang AJ, Chan LS.
Arch Dermatol. 2007 Feb;143(2):272-4. No abstract available.
A comprehensive management guide for atopic dermatitis.
Peterson JD, Chan LS.
Dermatol Nurs. 2006 Dec;18(6):531-42; quiz 543. Review. No abstract available.
Development of pemphigus herpetiformis in a patient with psoriasis receiving UV-light treatment.
Sanchez-Palacios C, Chan LS.
J Cutan Pathol. 2004 Apr;31(4):346-9.
Chan LS. Mucous membrane pemphigoid: past, present, and future. Ciornale Italiano di Dermatologia e Venereologia 138:207-218, 2003
Incontinentia pigmenti: a review and update on the molecular basis of pathophysiology.
Berlin AL, Paller AS, Chan LS.
J Am Acad Dermatol. 2002 Aug;47(2):169-87; quiz 188-90. Review.
Chan LS, Ahmed AR, Anhalt GJ, Bernauer W, Cooper KD, Elder MJ, Fine JD, Foster CS, Ghohestani R, Hashimoto T, Hoang-Xuan T, Kirtschig G, Korman NJ, Lightman S, Lozada-Nur F, Marinkovich MP, Mondino BJ, Prost-Squarcioni C, Rogers RS 3rd, Setterfield JF, West DP, Wojnarowska F, Woodley DT, Yancey KB, Zillikens D, Zone JJ.
Arch Dermatol. 2002 Mar;138(3):370-9. Review.
Chan LS.
Clin Dermatol. 2001 Nov-Dec;19(6):703-11. Review. No abstract available.
Schachter M, Brieva JC, Jones JC, Zillikens D, Skrobek C, Chan LS.
J Am Acad Dermatol. 2001 Nov;45(5):747-54.
Busquets AC, Jean-Baptiste S, Chan LS.
Br J Dermatol. 2001 Sep;145(3):510-2. No abstract available.
- PMID: 11531851 [PubMed – indexed for MEDLINE]
Chan LS.
Arch Dermatol. 2000 May;136(5):663-4. No abstract available.
- PMID: 10815861 [PubMed – indexed for MEDLINE]
Autoimmune blistering skin diseases.
Cotell S, Robinson ND, Chan LS.
Am J Emerg Med. 2000 May;18(3):288-99. Review.
Robinson ND, Hashimoto T, Amagai M, Chan LS.
J Am Acad Dermatol. 1999 May;40(5 Pt 1):649-71; quiz 672-3. Review.
- PMID: 10321591 [PubMed – indexed for MEDLINE]
Chan LS, Lapiere JC, Chen M, Traczyk T, Mancini AJ, Paller AS, Woodley DT, Marinkovich MP.
Arch Dermatol. 1999 May;135(5):569-73.
- PMID: 10328198 [PubMed – indexed for MEDLINE]
Lapiere JC, Guitart J, Ettlin DA, Chen DM, Amagai M, Chan LS.
Br J Dermatol. 1998 Nov;139(5):851-4.
Sporadic dystrophic epidermolysis bullosa with concomitant atopic dermatitis.
Lapinski P, Lapiere JC, Traczyk T, Chan LS.
Br J Dermatol. 1998 Feb;138(2):315-20.
Mancini AJ, Chan LS, Paller AS.
J Am Acad Dermatol. 1998 Feb;38(2 Pt 2):295-300. Review.
Treatment of refractory epidermolysis bullosa acquisita with extracorporeal photochemotherapy.
Gordon KB, Chan LS, Woodley DT.
Br J Dermatol. 1997 Mar;136(3):415-20.
Pemphigus foliaceus: preferential binding of IgG1 and C3 at the upper epidermis.
Hernandez C, Amagai M, Chan LS.
Br J Dermatol. 1997 Feb;136(2):249-52.
Porphyria cutanea tarda preceding AIDS.
Ash S, Woodley DT, Chan LS.
Lancet. 1996 Jan 20;347(8995):190. No abstract available.
- PMID: 8544558 [PubMed – indexed for MEDLINE]
Chan LS, Traczyk T, Taylor TB, Eramo LR, Woodley DT, Zone JJ.
Arch Dermatol. 1995 Dec;131(12):1432-7.
- PMID: 7492134 [PubMed – indexed for MEDLINE]
Burns MK, Chan LS, Cooper KD.
Arch Dermatol. 1995 Mar;131(3):325-9.
A nonscarring sublamina densa bullous drug eruption.
Roholt NS, Lapiere JC, Traczyk T, Chan LS, Woodley DT.
J Am Acad Dermatol. 1995 Feb;32(2 Pt 2):367-71.
- PMID: 7829742 [PubMed – indexed for MEDLINE]
Chan LS, Cooper KD.
Arch Dermatol. 1994 Mar;130(3):343-7.
- PMID: 8129413 [PubMed – indexed for MEDLINE]
Generalized autosensitization to a localized eczematoid dermatitis induced by ionizing radiation.
Roa WH, Gardiner DB, Krause BE, Chan LS.
J Am Acad Dermatol. 1994 Mar;30(3):489-90. No abstract available.
- PMID: 8113464 [PubMed – indexed for MEDLINE]
Chan LS, Yancey KB, Hammerberg C, Soong HK, Regezi JA, Johnson K, Cooper KD.
Arch Dermatol. 1993 Apr;129(4):448-55.
- PMID: 7682049 [PubMed – indexed for MEDLINE]
Chan LS, Dorman MA, Agha A, Suzuki T, Cooper KD, Hashimoto K.
J Am Acad Dermatol. 1993 Feb;28(2 Pt 2):331-5. Review.
- PMID: 8436652 [PubMed – indexed for MEDLINE]
Interferon alfa for linear IgA bullous dermatosis.
Chan LS, Cooper KD.
Lancet. 1992 Aug 15;340(8816):425. No abstract available.
- PMID: 1353573 [PubMed – indexed for MEDLINE]
Ocular cicatricial pemphigoid occurring as a sequela of Stevens-Johnson syndrome.
Chan LS, Soong HK, Foster CS, Hammerberg C, Cooper KD.
JAMA. 1991 Sep 18;266(11):1543-6.
- PMID: 1880886 [PubMed – indexed for MEDLINE]
Chan LS, Hanson CA, Cooper KD.
Arch Dermatol. 1991 Jun;127(6):862-5.
- PMID: 2036034 [PubMed – indexed for MEDLINE]
Chan LS, Hammerberg C, Cooper KD.
Arch Dermatol. 1990 Nov;126(11):1466-8.
- PMID: 2241199 [PubMed – indexed for MEDLINE]
Effects of cyclosporine on immunologic mechanisms in psoriasis.
Cooper KD, Voorhees JJ, Fisher GJ, Chan LS, Gupta AK, Baadsgaard O.
J Am Acad Dermatol. 1990 Dec;23(6 Pt 2):1318-26; discussion 1326-8. Review.
- PMID: 2277141 [PubMed – indexed for MEDLINE]
Koebnerization as a cutaneous manifestation of immune complex-mediated vasculitis.
Chan LS, Cooper KD, Rasmussen JE.
J Am Acad Dermatol. 1990 May;22(5 Pt 1):775-81.
- PMID: 2347963 [PubMed – indexed for MEDLINE]
Oral manifestations of linear IgA disease.
Chan LS, Regezi JA, Cooper KD.
J Am Acad Dermatol. 1990 Feb;22(2 Pt 2):362-5.
- PMID: 2406301 [PubMed – indexed for MEDLINE]
Coexistence of pemphigus vulgaris and progressive localized scleroderma.
Chan LS, Cooper KD.
Arch Dermatol. 1989 Nov;125(11):1555-7.
- PMID: 2817919 [PubMed – indexed for MEDLINE]
Epidermolysis bullosa acquisita in childhood. Differentiation from hereditary epidermolysis bullosa.
McCuaig CC, Chan LS, Woodley DT, Rasmussen JE, Cooper KD.
Arch Dermatol. 1989 Jul;125(7):944-9.
- PMID: 2662910 [PubMed – indexed for MEDLINE]