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Photo of Wardrop, Duncan

Duncan Wardrop, PhD

Associate Professor

Mentor, Drug Discovery and Development

Department of Chemistry

Contact

Building & Room:

4446 SES

Office Phone:

312-355-1035

About

Work in the Wardrop laboratory is focused on organic chemistry and specifically, on the development of new strategies and methods for the efficient synthesis of highly functionalized natural products and compounds with useful pharmacological properties. Current areas of interest include the chemistry of electron-deficient, divalent reactive intermediates, including nitrenium ions and alkylidenecarbenes and also the development of antiviral agents for the prophylaxis of haemorrhagic fevers, such as that caused by the Ebola virus. With regards to the latter project, we have recently discovered a potent, selective inhibitor of this highly pathogenic virus, which blocks its entry into human cell lines. Work is now underway, in collaboration with the UIC Department of Microbiology to elucidate the mode of action of this important molecule.