Terry Moore, PhD
Associate Professor
Mentor, Drug Discovery and Development
Department of Pharmaceutical Sciences
Contact
Building & Room:
504 PHARM
Office Phone:
Email:
About
Research in the Moore Lab focuses on developing small molecules and peptides that modulate transcription factor activity. His research group has an ongoing interest in the Nuclear factor E2-related factor 2 (Nrf2) signaling pathway. Nrf2 is the major transcription factor for detoxification enzymes that protect against oxidative and electrophilic stress. There is a substantial body of work that suggests that activation of Nrf2 may protect from neurodegeneration that results from oxidative stress. His laboratory is creating non-covalent, pharmacological Nrf2 activators, and these may eventually find utility as therapeutics for Alzheimer's and other neurodegenerative conditions.