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Photo of Moore, Terry

Terry Moore, PhD

Associate Professor

Mentor, Drug Discovery and Development

Department of Pharmaceutical Sciences

Contact

Building & Room:

504 PHARM

Office Phone:

312-413-1846

About

Research in the Moore Lab focuses on developing small molecules and peptides that modulate transcription factor activity. His research group has an ongoing interest in the Nuclear factor E2-related factor 2 (Nrf2) signaling pathway. Nrf2 is the major transcription factor for detoxification enzymes that protect against oxidative and electrophilic stress. There is a substantial body of work that suggests that activation of Nrf2 may protect from neurodegeneration that results from oxidative stress. His laboratory is creating non-covalent, pharmacological Nrf2 activators, and these may eventually find utility as therapeutics for Alzheimer's and other neurodegenerative conditions.