Yulia Komarova, PhD
Associate Professor
Mentor, Drug Discovery and Development
Department of Pharmacology and Regenerative Medicine
Contact
Building & Room:
COMRB 4053
Office Phone:
Email:
About
Dr. Komarova’s research focuses on endothelial physiology in health and disease. Specifically, her research examines the cross-talk between microtubule cytoskeleton and VE-cadherin-mediated adhesions in microvascular endothelial cells. Dynamic interaction between cytoskeleton and adherens junctions is known to be important for maintenance of basal endothelial barrier permeability and underlies changes in endothelial permeability in response to different mediators. Dr. Komarova investigates the molecular and signaling mechanisms regulating microtubule cytoskeleton downstream of adherens junction and how changes in microtubule dynamics affect integrity of endothelial monolayer in response to extracellular stimuli.