Leslie Aldrich, PhD
Assistant Professor
Department of Chemistry
About
Dr. Aldrich investigates topics at the interface of synthetic chemistry and biology with a focus on human health and disease. The goal is to discover and optimize small molecules to probe complex biological pathways and potentially identify novel therapeutic mechanisms. In addition, to develop small molecules that target specific autophagy proteins or protein-protein interactions and to explore the role of these proteins and interactions in the autophagy pathway and in various disease states, including inflammatory diseases, infectious diseases, lysosomal storage diseases, neurodegenerative diseases and aging. Her group's experience in synthetic chemistry, medicinal chemistry, biochemistry, cell biology, and high-throughput/high-content assay development enables them to explore highly interdisciplinary research topics.