Sang-Oh Yoon, PhD
Assistant Professor
Department of Physiology and Biophysics
Contact
Building & Room:
COMRB 2053
Office Phone:
Fax:
Lab
Building & Room:
COMRB 5068
Email:
Related Sites:
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The Yoon lab focuses on the regulation of cancer cell signaling and its functions in anti-cancer drug resistance, cell metabolism, and cell plasticity to form the basis of cancer therapeutics.
About
In order for cells to survive environmental stresses and maintain homeostatic balance, a complex cellular signaling network integrates information about the external and internal environment in order to allow for the cells to adapt. In cancer, dysregulation of signaling disrupts the normal and well-controlled physiological homeostasis. Altered signal transduction often provides cancer cells with advantages during periods of environmental stress and enables them to grow and metastasize. Our research interest is to biochemically and molecularly decode cancer cell signaling, especially PI3K/Akt/mTOR and Ras/Raf/ERK signaling networks that are used by cancer cells to support environmental stress resistance and cancer progression.