Alexandra Naba, PhD
Associate Professor
Mentor, Angiogenesis & Regeneration
Department of Physiology and Biophysics
Contact
Building & Room:
COMRB 2035
Office Phone:
Fax:
Lab
Building & Room:
COMRB 2048
Email:
Related Sites:
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The Naba laboratory uses cutting-edge proteomics and bioinformatics to study the role of the extracellular matrix (ECM) in development, health, and disease, with a particular focus on cancer.
About
The extracellular matrix (ECM), a complex meshwork of cross-linked proteins, is a fundamental components of multicellular organisms. It provides architectural supports to the cells, confers mechanical properties to tissues, and conveys biochemical signals transduced by cell surface receptors to control various cellular processes such as proliferation, survival, differentiation, adhesion and migration. In the Naba lab, we study the role of the ECM in development, health, and disease, with a particular focus on cancer. To do so, we utilize classical molecular, cellular, and developmental biology approaches in combination with cutting-edge proteomics and computational analyses. Our goal is to better understand how the ECM contributes to diseases so that we can exploit it to develop novel diagnostic and therapeutic strategies.