Chong Wee Liew, PhD
Associate Professor
Department of Physiology and Biophysics
Contact
Building & Room:
COMRB 2099
Office Phone:
Fax:
Lab
Building & Room:
COMRB 2108
Email:
Related Sites:
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Our lab focuses on understanding how adipose tissues regulate whole body metabolism and energy expenditure.
About
Adipose tissues (white, brown and beige) are constantly being remodeled to adapt to metabolic needs and environmental challenges. In response to a variety of hormonal, nutritional (e.g. fasting, overacting), environmental (cold exposure) cues, adipose tissues will undergo metabolic adaptation involving lipolysis, lipogenesis, adipogenesis, mitochondria biogenesis/clearance, and thermogenesis to regulate whole-body metabolic and energy homeostasis. Using cutting-edge technologies and multidisciplinary approaches (e.g. molecular biology, biochemistry, genetics, bioinformatics), we aims to understand/identify regulatory mechanisms modulated during physiological and patho-physiological perturbations. Our long-term goal is to use the insights we gain to contribute to new therapeutic strategies for the treatment of metabolic diseases (obesity, diabetes).