Andrei Karginov, PhD
Assistant Professor
Mentor
About
Dr. Karginov studies how endothelial barrier is regulated at the level of adherens junctions (AJs). He developed optogenetic and molecular tools to activate tyrosine kinases (e.g., Src) or phosphatases (PTPs and SHIP-1) at the single cell level, either promoting or disrupt VE-cadherin-mediated endothelial barrier function. Dr. Karginov expertise include developing biosensors, photo-activatable probes, and high-resolution imaging techniques.