Peter Kohl, MD, PhD – Freiburg University
November 1, 2024
12:00 PM - 1:00 PM
Host: R. John Solaro, PhD
The heart is an amazing organ. It beats once per second, about 2 billion times by the time we retire, and if it stops – so does life. Cardiac mechanical activity results from electrically-orchestrated contractions of billions of individual heart muscle cells, embedded within the extracellular matrix as the heart’s deformable skeleton, and interacting with cardiac nonmyocytes, whose numbers dwarf those of muscle cells. While much is known about cardiac structure-function cross-talk, the heart remains full of surprises. This lecture will reflect on some of them, across the nano to micro and macro scales, including published and unpublished material on convection-assisted exchange of transverse tubular system content, myocyte-nonmyocyte electrical interactions, and a potentially novel mechanism of post-reperfusion arrhythmogenesis in ventricular tissue.
Date posted
Sep 20, 2024
Date updated
Oct 28, 2024
Speakers
