Seminar – Joseph Zackular, PhD, University of Pennsylvania and Children’s Hospital of Philadelphia – Pathogen-microbiota interactions during Clostridioides difficile infection
University of Pennsylvania and Children's Hospital of Philadelphia
April 15, 2024
12:00 PM - 1:00 PM
Location
1020 COMRB
Calendar
Download iCal FileClostridioides difficile is the most commonly reported nosocomial pathogen in the United States and an urgent public health threat worldwide. The primary risk factor for C. difficile infection (CDI) is antibiotic use, which reduces colonization resistance to C. difficile by perturbing the gut microbiota. Despite the well-established link between the gut microbiota and susceptibility to C. difficile, the role of pathogen-microbiota interactions during CDI is largely unexplored. In this talk, I will discuss the effect of polymicrobial interactions on the outcome of CDI and investigate the molecular mechanisms of cross talk between C. difficile and members of the microbiota.
Date posted
Mar 7, 2024
Date updated
Apr 3, 2024
Speakers
