Geri Donenberg, PhD, and colleagues published findings from a two-arm randomized controlled trial comparing Trauma Informed Cognitive Behavioral Therapy enhanced to address HIV (TI-CBTe) to usual care (time-matched, long-standing, unstructured support groups) among youth living with HIV in Rwanda. TI-CBTe did not outperform usual care on ART adherence, possibly reflecting relatively high adherence at baseline, simplified medication regimens over time, a strong comparison condition, or because youth assigned to TI-CBTe returned to their support groups following the intervention. TI-CBTe was more effective for youth with lower depression/anxiety symptoms, whereas youth with high distress benefitted more from the support groups.
Donenberg GR, Fitts J, Ingabire C, Nsanzimana S, Fabri M, Emerson E, Remera E, Manzi O, Bray B, Cohen MH. Results of the Kigali Imbereheza Project: A 2-arm individually randomized trial of TI-CBT enhanced to address ART adherence and mental health for Rwandan youth living with HIV. J Acquir Immune Defic Syndr. 2022 Jan 8. doi: 10.1097/QAI.0000000000002911. Epub ahead of print. PMID: 35013089.