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UID:2026031502222520260303T11000020260303T12000069b617e1919eb@uic.edu
CATEGORIES:MEETING
STATUS:TENTATIVE
DTSTAMP:20260113T054601
DTSTART:20260303T110000
DTEND:20260303T120000
SUMMARY:Emily Hayes, MD/PhD Candidate (University of Illinois at Chicago): Thesis Defense
DESCRIPTION:Host: Carlos Stocco, PhD    Infertility affects millions of women worldwide, yet the molecular mechanisms regulating ovulation and ovarian function remain incompletely understood. This dissertation investigates the role of the salt-inducible kinases (SIKs), a family of serine/threonine kinases that modulate cAMP-dependent pathways, in ovarian follicle development. Using cell-specific genetic mouse models, this work defines distinct and opposing roles for SIK2 and SIK3 in granulosa and theca cells, revealing how these kinases regulate steroidogenesis and follicle maturation. Together, these findings identify SIK signaling as a critical regulator of gonadotropin responsiveness and provide new mechanistic insight into pathways that may contribute to ovulatory dysfunction and infertility. | Event post: https://chicago.medicine.uic.edu/physiology/events?page_id=2422
LOCATION:106 CMWT    Select 
CLASS:PRIVATE
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