Victoria L. Bautch, PhD (University of North Carolina): “LINCing the Nucleus to Endothelial Cell Function in Blood Vessels”
May 1, 2026
11:00 AM - 12:00 PM
Location
Moss Auditorium, 1020 COMRB
Calendar
Download iCal FileHost: Monica Lee, PhD
Endothelial cells that line blood vessels respond to blood flow-generated mechanical signals to the nucleus to function properly. Endothelial cell nuclear responses become less effective with age, leading to age-related vascular dysfunction and disease. We study how the endothelial cell nucleus integrates with the cytoskeleton via the LINC complex to transduce extracellular forces that regulate blood vessel function, such as shear stress from blood flow.
Date posted
Nov 17, 2025
Date updated
Mar 19, 2026
Speakers