Stryder Meadows, PhD (Tulane University): “Modeling second hit somatic mutations in HHT to uncover mechanisms of vascular pathologies and assess therapeutic strategies”
May 8, 2026
11:00 AM - 12:00 PM
Location
Moss Auditorium, 1020 COMRB
Calendar
Download iCal FileHost: Monica Lee, PhD
Our research utilizes advanced mouse models to investigate the molecular mechanisms of Hereditary Hemorrhagic Telangiectasia (HHT), a genetic disorder characterized by malformed blood vessels. We aim to dissect the key signaling pathways and factors that drive the formation of these vascular lesions in the retina and brain, and lead to vascular integrity deficits. Using high-resolution genomic sequencing, we have identified various factors with roles in promoting lesion development and demonstrate that targeting various pathways with pharmacologics can prevent and in some cases actively restore health to diseased vasculature, offering a promising path toward new therapies.
Date posted
Nov 17, 2025
Date updated
Mar 19, 2026
Speakers
