Ryan Petrie, PhD (Drexel University): “Powering the movement of human cells through 3D extracellular matrices”
April 24, 2026
11:00 AM - 12:00 PM
Location
Moss Auditorium, 1020 COMRB
Calendar
Download iCal FileHost: Alexandra Naba, PhD
Primary human fibroblasts can use at least two distinct mechanisms or modes of migration through three-dimensional (3D) matrices. We now find that this switch in migration mode is accompanied by significant changes in the distribution and dynamics of mitochondria in the migrating fibroblasts. We propose that perinuclear, stationary mitochondria generate the additional ATP required for fibroblasts to power the movement of the nucleus within cells migrating through crosslinked extracellular matrices.
Date posted
Sep 12, 2025
Date updated
Mar 19, 2026
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