Saif Aldeen Alryalat, MD
Assistant Professor
Department of Ophthalmology and Visual Sciences
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About
Dr. Saif Aldeen Alryalat is a dual-trained ophthalmologist with subspecialty expertise in Glaucoma and Anterior Segment Surgery (University of Colorado) and Neuro-ophthalmology (Houston Methodist Hospital and MD Anderson Cancer Center). He is recognized among the top 2% of researchers worldwide in ophthalmology, according to the Stanford's annual list, with a focus on the integration of artificial intelligence (AI) in ophthalmology. He is the author of the two-volume textbook Eye Yield, published by Springer Nature.
Selected Publications
Textbooks:
Alryalat, Saif Aldeen, ed. Ophthalmology Board and FRCS Part 2 Exams: Eye Yield Clinical. Springer Nature, 2025.
Alryalat, Saif Aldeen . Eye Yield: Ophthalmology Basics for Board and FRCS Part 1 Exams. Singapore: Springer Singapore, 2021.
Lee, A. G., Mortensen, P., Alryalat, S. A., & Al Deyabat, O. (Eds.). (2026). Neuro-Ophthalmology Update, An Issue of Neurologic Clinics: Neuro-Ophthalmology Update, An Issue of Neurologic Clinics, E-Book (Vol. 44, No. 2). Elsevier Health Sciences.
Journal articles:
Alryalat, Saif Aldeen, et al. “Structure–function correlates in anterior visual pathway lesions: a systematic review.” Eye (2025): 1-13.
Alryalat, Saif Aldeen, et al. “The diagnoses of glaucoma in the era of artificial intelligence.” Frontiers in Ophthalmology 4 (2024): 1496533.
Alryalat, Saif Aldeen, et al. “Predictors of visual acuity improvement after phacoemulsification cataract surgery.” Frontiers in Medicine 9 (2023): 894541.
Alryalat, Saif Aldeen, et al. “Deep learning prediction of response to anti-VEGF among diabetic macular edema patients: Treatment response analyzer system (TRAS).” Diagnostics 12.2 (2022): 312.
Alryalat, Saif Aldeen, et al. “Designs and methodologies used in landmark clinical trials of glaucoma: implications for future big data mining and actionable disease treatment.” Frontiers in Medicine 9 (2022): 818568.
Alryalat, Saif Aldeen. “Machine learning on glaucoma: the missing point.” Eye 35.9 (2021): 2456-2457.
Education
MD: The University of Jordan, Amman, Jordan
Internship: Jordan University Hospital
Residency in Ophthalmology: The University of Jordan
Fellowship in Neuro-Ophthalmology: MD Anderson Cancer Center, Houston, Texas
Fellowship in Neuro-Ophthalmology: Blanton Eye Institute, Houston Methodist Hospital
Fellowship in Glaucoma & Anterior Segment: University of Colorado