Pilot optimization trial of a sexual and reproductive health program for Latina teens and their female caregivers: A study protocol
New hybrid study tests an innovative intervention for Latina teens and their caregivers to improve sexual and reproductive health outcomes.
Dr. Katherine G. Merrill and colleagues are leading a hybrid type 2 mixed-methods study evaluating Floreciendo, a sexual and reproductive health intervention designed for Latina teens (ages 14–18) and their female caregivers. The program aims to address persistent health disparities in sexual and reproductive outcomes among Latina youth and families.
The study uses a pilot factorial experimental design, drawing from the Multiphase Optimization Strategy (MOST) framework. Across four community partner organizations (CPOs), 92 teen-caregiver pairs (184 participants) will be randomized into one of eight study conditions. All groups will receive the Foundations in Sexual Risk Prevention component, while other modules—Condoms and Contraception, Family Strengthening, and Gender and Relationships—will vary across groups to assess feasibility, acceptability, and early signals of effectiveness.
The research team will also examine implementation outcomes such as feasibility, adoption, cost, and fidelity, supplemented by qualitative interviews with Latina teens, caregivers, facilitators, and community partners.
Why it matters:
This pilot trial represents a crucial step toward developing a culturally responsive, family-based program to reduce sexual risk behaviors and promote healthy communication in Latina families. Findings will inform the design of a fully powered optimization trial of Floreciendo.
