Lei Bao, PhD

Research Assistant Professor
Photo of Lei Bao PhD

Biographical Info

Research Assistant Professor


Graduate School:  University of Illinois College of Medicine, PhD in Physiology

Post-doctoral:  University of Illinois at Chicago



Dr. Bao’s publications are depicted below, starting from the most recent papers: 

A molecular mechanism for IL-4 suppression of loricrin transcription in epidermal keratinocytes: implication for atopic dermatitis pathogenesis.

Bao L, Mohan GC, Alexander JB, Doo C, Shen K, Bao J, Chan LS.

Innate Immun. 2017 Nov;23(8):641-647. doi: 10.1177/1753425917732823. Epub 2017 Sep 27.

PMID: 28952836
Involucrin expression is downregulated in the skin of IL-4 transgenic mice.
Bao L, Alexander JB, Zhang H, Shen K, Chan LS.
J Interferon Cytokine Res. 2017 Apr;37(4):cover art.

Diacerein inhibits the pro-atherogenic & pro-inflammatory effects of IL-1 on human keratinocytes & endothelial cells.

Mohan GC, Zhang H, Bao L, Many B, Chan LS.

PLoS One. 2017 Mar 21;12(3):e0173981. doi: 10.1371/journal.pone.0173981. eCollection 2017.

PMID: 28323859

Interleukin-4 Downregulation of Involucrin Expression in Human Epidermal Keratinocytes Involves Stat6 Sequestration of the Coactivator CREB-Binding Protein.

Bao L, Alexander JB, Zhang H, Shen K, Chan LS.

J Interferon Cytokine Res. 2016 Jun;36(6):374-81. doi: 10.1089/jir.2015.0056. Epub 2016 Feb 26.

PMID: 26918372

Differential expression of inflammation-related genes in IL-4 transgenic mice before and after the onset of atopic dermatitis skin lesions.

Bao L, Zhang H, Mohan GC, Shen K, Chan LS.

Mol Cell Probes. 2016 Feb;30(1):30-8. doi: 10.1016/j.mcp.2015.11.001. Epub 2015 Nov 14.

PMID: 26585782

Aberrant Wound Healing in an Epidermal Interleukin-4 Transgenic Mouse Model of Atopic Dermatitis.

Zhao Y, Bao L, Chan LS, DiPietro LA, Chen L.

PLoS One. 2016 Jan 11;11(1):e0146451. doi: 10.1371/journal.pone.0146451. eCollection 2016.

PMID: 26752054

Interleukin-4 up-regulation of epidermal interleukin-19 expression in keratinocytes involves the binding of signal transducer and activator of transcription 6 (Stat6) to the imperfect Stat6 sites.

Bao L, Alexander JB, Shi VY, Mohan GC, Chan LS.

Immunology. 2014 Dec;143(4):601-8. doi: 10.1111/imm.12339.

PMID: 24943510

The involvement of the JAK-STAT signaling pathway in chronic inflammatory skin disease atopic dermatitis.

Bao L, Zhang H, Chan LS.

JAKSTAT. 2013 Jul 1;2(3):e24137. doi: 10.4161/jkst.24137. Epub 2013 Aug 15. Review.

PMID: 24069552

IL-4 up-regulates epidermal chemotactic, angiogenic, and pro-inflammatory genes and down-regulates antimicrobial genes in vivo and in vitro: relevant in the pathogenesis of atopic dermatitis.

Bao L, Shi VY, Chan LS.

Cytokine. 2013 Feb;61(2):419-25. doi: 10.1016/j.cyto.2012.10.031. Epub 2012 Dec 1.

PMID: 23207180

Inflammation-driven dermal lymphangiogenesis in atopic dermatitis is associated with CD11b+ macrophage recruitment and VEGF-C up-regulation in the IL-4-transgenic mouse model.

Shi VY, Bao L, Chan LS.

Microcirculation. 2012 Oct;19(7):567-79. doi: 10.1111/j.1549-8719.2012.00189.x.

PMID: 22574929

IL-4 regulates chemokine CCL26 in keratinocytes through the Jak1, 2/Stat6 signal transduction pathway: Implication for atopic dermatitis.

Bao L, Shi VY, Chan LS.

Mol Immunol. 2012 Feb;50(1-2):91-7. doi: 10.1016/j.molimm.2011.12.008. Epub 2012 Jan 5.

PMID: 22226123

Inhibition of MAPK by prolactin signaling through the short form of its receptor in the ovary and decidua: involvement of a novel phosphatase.

Devi YS, Seibold AM, Shehu A, Maizels E, Halperin J, Le J, Binart N, Bao L, Gibori G.
J Biol Chem. 2011 Mar 4;286(9):7609-18. Epub 2011 Jan 3.

Involvement of cyclin D3, CDKN1A (p21), and BIRC5 (Survivin) in interleukin 11 stimulation of decidualization in mice.

Li F, Devi YS, Bao L, Mao J, Gibori G.
Biol Reprod. 2008 Jan;78(1):127-33. Epub 2007 Sep 19.

Decidual prolactin silences the expression of genes detrimental to pregnancy.

Bao L, Tessier C, Prigent-Tessier A, Li F, Buzzio OL, Callegari EA, Horseman ND, Gibori G.
Endocrinology. 2007 May;148(5):2326-34. Epub 2007 Jan 25.

The role of interleukin-11 in pregnancy involves up-regulation of alpha2-macroglobulin gene through janus kinase 2-signal transducer and activator of transcription 3 pathway in the decidua.

Bao L, Devi S, Bowen-Shauver J, Ferguson-Gottschall S, Robb L, Gibori G.
Mol Endocrinol. 2006 Dec;20(12):3240-50. Epub 2006 Sep 7.

Decidual activin: its role in the apoptotic process and its regulation by prolactin.

Tessier C, Prigent-Tessier A, Bao L, Telleria CM, Ferguson-Gottschall S, Gibori GB, Gu Y, Bowen-Shauver JM, Horseman ND, Gibori G.
Biol Reprod. 2003 May;68(5):1687-94. Epub 2002 Dec 11.

Diagnosis, treatment and prognosis of renal cancer with tumor thrombus in inferior vena cava with cases report.
Boa L, Yuan J, Xu F.
Beijing Medical J. 1999; 21:327-329.

A case report of renal cancer that is difficult to differentiate from renal angiolipoleiomyoma.Bao L, Ji Z, Xu F.
Chin J Surg. 1999; 37:285.

Diagnosis, treatment and prognosis of renal cancer with tumor thrombus in inferior vena cava (review).
Bao L, Yuan J, Xu F, Ao M, Zang M.
Jiangsu J of Chinese Traditional Medicine. 1998; Suppl: 84-86.

The tasks of clinical nutrition.
Bao L, Yu J, Jiang Z.
Chin J Clin Nutri. 1995; 3:3-8.

How to evaluate surgical patients’ nutritional status.
Bao L, Yu J.
Guo Wai Yi Xue, Surgery Section. 1994; 4:162-163.

Categories: Department of Dermatology