John Karl Frederiksen, M.D., Ph.D.
Assistant Professor Director, Hematology Laboratory University of Illinois at ChicagoPathologyBiographical Info
Clinical Focus
Hematopathology
Research and Educational Focus
Hematopathology, hematology test utilization
Education:
Stanford University (B.S., Chemistry)
University of Chicago Pritzker School of Medicine (M.D.)
University of Chicago (Ph.D., Biochemistry and Molecular Biology)
Post-Graduate Training:
Residency
University of Rochester Medical Center (Anatomic and Clinical Pathology)
Fellowship
University of Michigan Medical Center (Hematopathology)
University of Miami Miller School of Medicine (Molecular Genetic Pathology)
Board Certification:
Anatomic and Clinical Pathology
Hematology
Molecular Genetic Pathology
Awards and Honors:
Best Teacher in the Pathology Residency Program, SUNY Upstate Medical University (2019-2020)
Teacher of the Year, University of Illinois at Chicago Pathology Residency Program (2022)
Selected Recent Publications:
Qu, C., Kunkalla, K., Vaghefi, A., Frederiksen, J. K., Liu, Y., Chapman, J. R., Blonska, M., Bernal-Mizrachi, L., Alderuccio, J. P., Lossos, I. S., Landgraf, R. & Vega, F. (2018). Smoothened stabilizes and protects TRAF6 from degradation: A novel non-canonical role of smoothened with implications in lymphoma biology. Cancer Lett 436, 149-158 (PubMed ID 30165192).
Choi, S. M., Frederiksen, J. K., Ross, C. W., Bixby, D. L. & Shao, L. (2017). Philadelphia Chromosome-like Mixed-Phenotype Acute Leukemia Demonstrating P2RY8-CRLF2 Fusion and JAK1 Mutation. Am J Clin Pathol 148, 523-528 (PubMed ID 29140408).
Weindorf, S. C. & Frederiksen, J. K. (2017). IgG4-Related Disease: A Reminder for Practicing Pathologists. Arch Pathol Lab Med 141, 1476-1483 (PubMed ID 29072949).
Frederiksen, J. K., Shao, L., Bixby, D. L. & Ross, C. W. (2016). Shared clonal cytogenetic abnormalities in aberrant mast cells and leukemic myeloid blasts detected by single nucleotide polymorphism microarray-based whole-genome scanning. Genes Chromosomes Cancer 55, 389-396 (PubMed ID 26865278).
Frederiksen, J. K., Sharma, M., Casulo, C. & Burack, W. R. (2015). Systematic review of the effectiveness of fine-needle aspiration and/or core needle biopsy for subclassifying lymphoma. Arch Pathol Lab Med 139, 245-251 (PubMed ID 25611108).
Frederiksen, J. K. & Ross, C. W. (2014). Cytomegalovirus-associated hemophagocytic lymphohistiocytosis in a patient with myasthenia gravis treated with azathioprine. Blood 123, 2290 (PubMed ID 24895699).