Xiaohong Joe Zhou, PhD, DABRDirector of Center for MR Research; Professor of Radiology, Neurosurgery, and Bioengineering; Chief Medical Physicist
The research in my group is focused primarily on developing diffusion imaging techniques to improve cancer diagnosis, guide surgery, and monitor treatment efficacy. We are particularly interested in developing non-EPI-based data acquisition techniques to achieve high spatial resolution. With the high resolution capability, we are presently exploring a number of applications, including tracking tumor cell infiltration along the white-matter fiber tracts, early detection of tumor recurrent sites, and probing tissue cellularity change during radiation therapy. Our group is also interested in selective phosphorus imaging at ultra-high field. We are presently developing efficient RF pulses for 31P selective excitation, and will use the technique to map the 3D distribution of important metabolites, such as phosphorus creatine at 9.4T. The ultimate goal of this project is to develop a robust metabolic imaging marker for human applications.