Background: A cerebrospinal fluid (CSF) leak from the nose is termed CSF rhinorrhea. Forty percent of cases are idiopathic, meaning the cause is unknown. Numerous studies have demonstrated that the best way to repair CSF rhinorrhea is to utilize multiple layers of closure. Nevertheless, even after an optimal repair, some patients have persistent CSF rhinorrhea. There is a lack of information and understanding regarding the wound healing process involving CSF [...]
Background: There is a need to prospectively collect outcomes data on patients with sinonasal pathology. Such a database is extremely useful as it provides a continuously expanding resource for research projects and data mining. Objective: To develop a REDCap sinonasal outcomes database to prospectively collect standardized clinical outcomes information on patients presenting to UIC with sinonasal pathology.
Background: It is important from a surgical planning standpoint to continue identifying anatomic variants on imaging that have relevance to surgical planning. In our experience, certain variants are commonly seen but underreported in the literature, and this is the focus of these research efforts. Objective: To evaluate specific anatomic characteristics on imaging important for endonasal endoscopic approaches, in particular defining them, determining their prevalence, and identifying associated features. [...]
Background: Viral upper respiratory infections can progress to sinusitis and contribute to sinonasal symptom exacerbations, resulting in significant morbidity. Objective: To characterize the immune response of various sinonasal cell types when exposed to viral upper respiratory pathogens.
Background: Idiopathic intracranial hypertension is a syndrome of high intracranial pressure of unclear cause. There is increasing evidence associating the presence of idiopathic intracranial hypertension with the incidence of spontaneous cerebrospinal fluid leaks. Objective: Evaluate the association of idiopathic intracranial hypertension and spontaneous cerebrospinal fluid leaks using a novel institutional diagnostic protocol
Background: Allergic and non-allergic rhinitis, rhinosinusitis, and asthma are poorly understood diseases that affect millions of people each year. These conditions co-exist in many patients and often, onset of one is associated with exacerbation of the other. The apparent relationship of the diseases has led to the consideration of the controversial 'one airway' theory. The key, or link to understanding the relationship and cause of these various diseases may be [...]