Head & Neck Surgery2020-10-09T11:47:58-05:00


A Phase 3, Randomized, Double-Arm, Open-Label, Controlled Trial of ASP-1929 Photoimmunotherapy Versus Physician’s Choice Standard of Care for the Treatment of Locoregional, Recurrent Head and Neck Squamous Cell Carcinoma in Patients Who Have Failed or Progressed on or After Two Lines of Therapy, Wenig.B, Achim.V

Background: Photoimmunotherapy (PIT) is a new cancer-targeted therapy. PIT is a combination drug and device anti-cancer treatment that utilizes monoclonal antibodies conjugated to a dye, that can be activated upon nonthermal 690 nm red light illumination to induce rapid cell death only at cells expressing the antigen and only after antibody binding to the cellular antigen. The requirement of light-induced activation and antigen-antibody binding to induce cell death enables the selective and specific destruction of tumor cells with minimum [...]

Antibiotic Usage in Head and Neck Cancer Surgery, Achim.V, Brown.L

Background: Widespread antibiotic usage has led to an increase in antibiotic resistant bacteria and an increase in allergies to antibiotics. Penicillin antibiotics have been the gold standard for head and neck surgical prophylaxis, but unfortunately, more and more patients have developed allergies to this antibiotic. Currently, surgical antibiotic prophylaxis for head and neck cancer patients varies from institution to institution, as well as between surgeons of the same institution. To date, no one antibiotic regimen has been found to [...]

Evaluating the Use of an Informational Head and Neck Cancer Website for Patient and Family Education, Achim.V, Brown.L

Background: It can be difficult for head and neck cancer patients and their families to fully understand the impact that cancer procedures and treatments can have on a cancer patient’s life. Procedures used to treat head and neck cancer may result in significant changes to the patients’ physical appearance and/or functional abilities (talking, eating, and breathing). Lack of understanding as it relates to the effects of cancer treatments can have a significant impact on the patient’s post-operative success. In [...]

Evaluating the Use of Myofascial Release in the Management of Muscle Fibrosis in Head and Neck Cancer Patients, Achim.V, C.Deskin SLP

Background: Patients who have undergone head and neck cancer treatment, often develop post-treatment associated muscle damage. The resulting muscle damage has a long lasting effect on range of motion (ROM) and swallow dysfunction. This is a common early and late sequela following either surgery-based or radiation-based therapy for head and neck cancer (HNC). The treatment related toxicity is strongly correlated with reduced quality of life. Myofascial release (MFR) therapy is an accepted treatment modality by physical therapists and speech [...]

Incidence of Venous Thromboembolism in Head and neck Cancer Patients After Resection and Microvascular Free Flap Reconstruction, Wenig.B

Background: Venous thromboembolism (VTE) is a disease process characterized by blood clot formation in the deep veins of the lower extremities, known as deep vein thrombosis. In some, a blood clot may dislodge and travel into the vessels of the lungs causing a pulmonary embolism (PE). The incidence of this disease is increased by factors that 1) cause damage to blood vessels, 2) decrease blood circulation, and 3) increase thickness of the blood. Head and neck cancer patients who [...]

Perioperative Nutritional Optimization in Head and Neck Cancer Patients. Achim.V, S. Scheeler RN

Background: Delayed or poor post-operative wound healing accounts for the majority of complications associated with major head and neck surgery. These complications lead to increased length of hospital stay, increased hospital costs, and delayed adjuvant treatment such as radiation and chemotherapy. The head and neck cancer population is especially vulnerable to malnutrition; many of these patients experience dysphagia and odynophagia as cancer related symptoms due to the location of the primary tumor. Even in the absence of these symptoms, [...]

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