Beatrice Y.J.T. Yue, PhD, Director
Thanis A. Field Professor of Ophthalmology and Visual Sciences
Characterization and functions of glaucoma genes optineurin and myocilin, as well as biology of trabecular meshwork cells.
Current investigations center on optineurin, a gene associated with normal tension glaucoma, in particular examining the cellular processing of optineurin in neuronal cells.
Glaucoma is a major blinding disease. Results obtained from the research programs will provide insights into the basic biology of optineurin and myocilin, help illustrate how glaucoma is developed, and lead to novel therapeutic modalities for this disease.