Research Interest:

Investigates the pathology of corneal wound healing, the role of matrix metalloproteinases in the cornea, and mathematical modeling and optics in refractive surgery and presbyopic treatments.

Ongoing Research:

Current investigations focus on the stromal fibroblasts promotion of corneal neovascularization through their proangiogenic MMP activity.

Impact:

Characterization of the spatial and temporal relationships of MT1-MMP activity in corneal angiogenesis and evaluation of the mechanisms of corneal neovascularization will be valuable for identifying potential targets for therapeutic intervention in the treatment of corneal neovascularization.