Professor of Ophthalmology, Retina Service
Cless Family Professor in Ophthalmology
Vice Chair for Faculty Affairs
Director, Ocular Oncology Clinic
Director, Residency and Vitreoretinal Fellowship Training
Board of Trustees and President-elect, Association for Research in Vision and Ophthalmology (ARVO)
Sees Patients at:
Specialty Care Building (SCB)
1009 S. Wood St.
Chicago, IL 60612
Schedule an Appointment
Millennium Park Eye Center (MPEC)
30 N. Michigan Avenue, Suite 410
Chicago, IL 60602
Phone: (312) 996-2020
Dr. Mieler is an expert in treating diseases of the macula, retina and vitreous. His primary research interests are ocular pharmacology, exploring drug delivery to the posterior segment of the eye, uptake and potential toxicity of topical, periocular and systemic medications, intraocular tumors and response to therapy and ocular imaging. He also participates in numerous national clinical trials for the treatment of age-related macular degeneration, diabetic macular edema, venous occlusive diseases and vitreoretinal interface disorders. Dr. Mieler received the Life Achievement Honor Award from the American Board of Ophthalmology (AAO) and served as its director, vice-chair and chair. He is a past president of the Macula Society, which awarded the 2013 J. Donald Gass Medal to him for his outstanding contributions to the study of macular diseases. He has published 330 peer-reviewed articles, 70 book chapters and edited or co-edited six ophthalmic textbooks. He has delivered 19 named lectures, served on editorial boards for three ophthalmic journals and is a reviewer for 22 additional journals. He is Retina Section Trustee and President-Elect of the Association for Research in Vision and Ophthalmology (ARVO). Dr. Mieler also served on several committees of the American Board of Medical Specialties. He joined the Illinois Eye and Ear Infirmary in 2008. Dr. Mieler is board certified in ophthalmology.
Dr. William Mieler, MD, recognized for extraordinary contributions to diseases of the macula
Dr. William Mieler elected to lead vision research organization
BS—University of Wisconsin-Madison, elected to Phi Kappa Phi
MD—University of Wisconsin-Madison Medical School, elected to Alpha Omega Alpha
Residency—Bascom Palmer Eye Institute, University of Miami
Clinical Fellowship in Retina-Vitreous—The Eye Institute, Medical College of Wisconsin
Clinical Fellowship in Ocular Oncology—Wills Eye Hospital, Thomas Jefferson University, Philadelphia
Selected Honors and Awards
Castle Connolly Top Doctors 2003 – 2013
Chicago Top Doctors 2006, 2008, 2010, 2012, 2014
Chicago Super Doctors 2012, 2013
Best Doctors in America 1995 – 2014
American Academy of Ophthalmology
• Life Achievement Honor Award, 2011
• Lifelong Education for the Ophthalmologist Continuing Education Recognition Award, 2011
• Senior Achievement Award, 2001
• Achievement Award, 1992
American Society of Retina Specialists
• Founders Award, 2011
• Crystal Apple Award, 2005
See a representative list of Dr. Mieler’s published journal articles in PubMed.
Guthrie MJ, Osswald CR, Valio NL, Mieler WF, Kang-Mieler JJ. Objective area measurement technique for choroidal neovascularization from fluorescein angiography. Microvasc Res. 2014 Jan;91:1-7. doi: 10.1016/j.mvr.2013.11.005. Epub 2013 Dec 5. PubMed PMID: 24316422.
Drapala PW, Jiang B, Chiu YC, Mieler WF, Brey EM, Kang-Mieler JJ, Pérez-Luna VH. The Effect of Glutathione as Chain Transfer Agent in PNIPAAm-Based Thermo-responsive Hydrogels for Controlled Release of Proteins. Pharm Res. 2013 Sep 11. [Epub ahead of print] PubMed PMID: 24022682.
Dikopf MS, Chow CC, Mieler WF, Tu EY. Cataract extraction outcomes and the prevalence of zonular insufficiency in retinitis pigmentosa. Am J Ophthalmol. 2013 Jul;156(1):82-88.e2. doi: 10.1016/j.ajo.2013.02.002. Epub 2013 Apr 28. PubMed PMID: 23628349.
Jivrajka RV, Genead MA, McAnany JJ, Chow CC, Mieler WF. Microperimetric sensitivity in patients on hydroxychloroquine (Plaquenil) therapy. Eye (Lond).2013 Jun 14. doi: 10.1038/eye.2013.112. [Epub ahead of print] PubMed PMID: 23764990.
Patel KH, Chow CC, Rathod R, Mieler WF, Lim JI, Ulanski LJ 2nd, Leiderman YI,Arun V, Chau FY. Rapid response of retinal pigment epithelial detachments to intravitreal aflibercept in neovascular age-related macular degeneration refractory to bevacizumab and ranibizumab. Eye (Lond). 2013 May;27(5):663-7; quiz 668. doi: 10.1038/eye.2013.31. Epub 2013 Apr 5. PubMed PMID: 23558214; PubMed Central PMCID: PMC3650278.
Schwartz SG, Flynn HW Jr, Mieler WF. Update on retinal detachment surgery.Curr Opin Ophthalmol. 2013 May;24(3):255-61. doi: 10.1097/ICU.0b013e32835f8e6b. Review. PubMed PMID: 23429600.
Nguyen QD, Campochiaro PA, Shah SM, Browning DJ, Hudson HL, Sonkin PL, Hariprasad SM, Kaiser PK, Slakter J, Haller JA, Do DV, Mieler W, Chu K, Ingerman A, Vitti R, Berliner AJ, Cedarbaum J; Clear-It 1 Investigators. Evaluation of very high- and very low-dose intravitreal aflibercept in patients with neovascular age-related macular degeneration. J Ocul Pharmacol Ther. 2012 Dec;28(6):581-8. doi: 10.1089/jop.2011.0261. Epub 2012 Jul 9. PubMed PMID: 22775078.
Kiernan DF, Mieler WF. Intraocular corticosteroids for posterior segment disease: 2012 update. Expert Opin Pharmacother. 2012 Aug;13(12):1679-94. doi: 10.1517/14656566.2012.690736. Epub 2012 Jul 12. Review. PubMed PMID: 22783878.
Kiernan DF, Zelkha R, Hariprasad SM, Lim JI, Blair MP, Mieler WF. En face spectral-domain optical coherence tomography outer retinal analysis and relation to visual acuity. Retina. 2012 Jun;32(6):1077-86. doi:10.1097/IAE. 0b013e31823c23bc. PubMed PMID: 22466459; PubMed Central PMCID: PMC3707390.
McLeod R, Boyer KM, Lee D, Mui E, Wroblewski K, Karrison T, Noble AG, Withers S, Swisher CN, Heydemann PT, Sautter M, Babiarz J, Rabiah P, Meier P, Grigg ME; Toxoplasmosis Study Group. Prematurity and severity are associated with Toxoplasma gondii alleles (NCCCTS, 1981-2009). Clin Infect Dis. 2012 Jun;54(11):1595-605. doi: 10.1093/cid/cis258. Epub 2012 Apr 11. PubMed PMID: 22499837; PubMed Central PMCID: PMC3348955.
Mieler WF, Kang-Mieler JJ. Something about Larry. Retina. 2012 Feb;32 Suppl 1:S27-8. doi: 10.1097/IAE. 0b013e318240a4df. PubMed PMID: 22270781.
Haller JA, Bandello F, Belfort R Jr, Blumenkranz MS, Gillies M, Heier J, Loewenstein A, Yoon YH, Jiao J, Li XY, Whitcup SM; Ozurdex GENEVA Study Group, Li J. Dexamethasone intravitreal implant in patients with macular edema related to branch or central retinal vein occlusion twelve-month study results. Ophthalmology. 2011 Dec;118(12):2453-60. doi: 10.1016/j.ophtha.2011.05.014. Epub 2011 Jul 20. PubMed PMID: 21764136.
Kiernan DF, Shah RJ, Hariprasad SM, Grassi MA, Small KW, Kiernan JP, Mieler WF. Thirty-Year follow-up of an African American family with macular dystrophy of the retina, locus 1 (North Carolina macular dystrophy). Ophthalmology. 2011 Jul;118(7):1435-43. doi: 10.1016/j.ophtha.2010.10.041. Epub 2011 Feb 18. PubMed PMID: 21310494.
Turturro SB, Guthrie MJ, Appel AA, Drapala PW, Brey EM, Pérez-Luna VH, Mieler WF, Kang-Mieler JJ. The effects of cross-linked thermo-responsive PNIPAAm-based hydrogel injection on retinal function. Biomaterials. 2011 May;32(14):3620-6. doi: 10.1016/j.biomaterials.2011.01.058. Epub 2011 Feb 12. PubMed PMID: 21320724.
Marmor MF, Kellner U, Lai TY, Lyons JS, Mieler WF; American Academy of Ophthalmology. Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy. Ophthalmology. 2011 Feb;118(2):415-22. doi: 10.1016/j.ophtha.2010.11.017. PubMed PMID: 21292109.