Nicola Winston2017-10-16T13:52:17+00:00
Nicola Winston

Nicola Winston, PhD, HCLD

Clinical Associate Professor of Obstetrics & Gynecology,
Laboratory Director University of Illinois at Chicago IVF Program

Phone: (312) 355-0458

 

Biography

Dr. Nicola Winston  is the Laboratory Director for the University of Illinois In Vitro Fertilization (IVF) Program. She provides professional consultation to physicians and patients regarding clinical embryology and treatment outcomes, as well as teaching students, residents and fellows the intricacies of early human development.

Dr. Winston’s research focuses on the process of egg maturation and improving our understanding of events that occur during ovarian follicle and oocyte growth and maturation.  Her studies have also sought to identify and describe the function of factors involved in the regulation of early embryo development. Answering the question “How do these processes impact subsequent oocyte and embryo viability?” will greatly enhance the success of infertility treatments using assisted reproduction technologies.

Publications 

Baumgarten S, Convissar SM, Zamah AM, Fierro M, Winston NJ, Scoccia B, and Stocco C. “FSH regulated IGF-2 expression in human granulosa cells in an AKT-dependent manner”. Journal of Clinical Endocrinology & Metabolism2015;100(8): E1046-1055.

Baumgarten SC, Convissar SM, Fierro MA, Winston NJ, Scoccia B, Stocco C. “IGF1R signaling is necessary for FSH-induced activation of AKT and differentiation of human cumulus granulosa cells”.  Journal of Clinical Endocrinology & Metabolism, 2014;99(8): 2995-3004.

Zhou P, Baumgarten SC, Wu Y, Bennett J, Winston NJ, Hirshfeld-Cytron J, Stocco C.  “IGF-1 signaling is essential for FSH stimulation of AKT and steroidogenic genes in granulosa cells”. Molecular Endocrinology 2013;27(3): 511-523.

Recent Abstracts and Presentations

Zamah AM, Baumgarten SC, Convissar S, Fierro MA, Winston NJ, Stocco C, Scoccia B.: “FSH regulated IGF2 expression in human granulosa cells in an AKT-dependent manner.” Podium presentation at the 71st Annual Meeting of the American Society for Reproductive Medicine, Baltimore, MD. October 17-21, 2015.

Zamah AM, Baumgarten SC, Winston NJ, Stocco C, Scoccia B: “FSH receptor and IGF-1 receptor coordinated activation of AKT is essential for human granulosa cell differentiation”. Presented at the 70th Annual Meeting of the American Society for Reproductive Medicine, Honolulu, Hawaii, October 18-22, 2014.

Baumgarten SC, Convissar SM, Fierro MA, Winston NJ, Zamah AM, Scoccia B, Stocco C: “Follicle stimulating hormone differentially regulates gene expression through AKT and ERK1/2 activation in human granulosa cells”. Presented at the 70th Annual Meeting of the American Society for Reproductive Medicine, Honolulu, Hawaii, October 18-22, 2014.

Baumgarten SC, Convissar S, Fierro M, Winston N, Scoccia B, Stocco C.: “Follicle stimulating hormone regulates insulin-like growth factor 2 expression in human granulosa cells in an AKT-dependent manner”. Platform presentation at the Annual Meeting of the Society for the Study of Reproduction, Grand Rapids, MI. July 19-23, 2014.

Fierro M, Scoccia, B, Winston NJ. “Do insurance company guidelines restricting Intracytoplasmic Sperm Injection (ICSI) use affect IVF treatment outcomes in a mandated state?” Poster presented at the Annual Meeting of the College of Reproductive Biology (ABB) Annual Meeting, Las Vegas, NV. May 16-18, 2013

Scoccia B, Bernardi LA, Alvarez JP, Fierro MA, Winston NJ.: “Significant TSH changes induced by estrogen and progesterone administration in hypothyroid patients undergoing preparation for frozen embryo transfer” Poster presentation at the Annual Meeting of the American Society for Reproductive Medicine, Oct. 12-17, 2013.

Baumgarten SC, Zhou P, Fierro M, Winston N, Hirshfeld-Cytron J, Stocco C.: “A novel approach to study human granulosa cell differentiation reveals FSH induction of key differentiation genes depends on the activity of the insulin-like growth factor-1 receptor.” Podium presentation at the 46th Annual Meeting of Society for the Study of Reproduction., Montreal, CA, July 22-26, 2013.

Hirshfeld-Cytron J, Winston N, Scoccia B. “Fertility preservation decision making in an urban patient population.” Poster presentation at the 60th Annual Meeting of Society for Gynecologic Investigation, Orlando, Fl, March 20-23, 2013.