Studies Open to Enrollment

Network Epidemiology of Syphilis Transmission (NEST) Phase 1: Pilot

NEST is being conducting to address the syphilis epidemic occurring across the United States.  By administering an online questionnaire to participants, this study seeks to understand how social and sexual contacts, sexual behavior and health care utilization contribute to new syphilis infections among MSM in Chicago.

This study hopes to enhance public health interventions to reduce syphilis transmission. Despite syphilis being a clinically relevant disease for centuries, we continue to lack knowledge regarding the immune response to syphilis. Current diagnostic testing lacks distinction between new and previously treated syphilis infection.

As a component of this study, participant blood, urine and saliva will be collected to study the immune response to enhance current diagnostic testing for syphilis.

UIC Principal Investigator/s: Richard M. Novak M.D and Andrew Trotter, MD, MPH

Study Coordinator: Kristin Boyce, RN

Community Affairs Specialist: Anthony Johnson, MPH

HPTN 083

HPTN 083: Investigational HIV drug

HPTN 083 is a study being done to evaluate the efficacy of the long-acting injectable agent for pre-exposure prophylaxis (PrEP) in HIV-uninfected men and transgender women who have sex with men (MSM and TGW).

The main purpose of this clinical research trial is to see if cabotegravir, an antiretroviral medication can prevent infection with HIV in persons at high risk for HIV infection.

The study will last 1.5 – 3 years and you may be eligible if you are:

  • 18 years of age or older
  • HIV negative
  • Sex assigned at birth was male
  • Gender – male or trans female
  • Have sex with men

This study is a double-blind study – all participants receive active medication but neither they nor the study staff will be aware of which medication they are getting.  All participants will receive an injection every 2 months and oral tablets that are taken once daily.

Participants will be compensated for their time and will receive regular HIV testing and counseling, condoms and lubricant.

If you are interested in this study – please contact Project WISH to arrange for a phone screen at 312-413-5897

UIC Principal Investigator/s: Richard M. Novak M.D and Stockton Mayer, DO

Study Coordinator: Stephanie Martin, RN, BA

Community Affairs Specialist: Anthony Johnson, MPH

REPRIEVE Randomized Trial to Prevent Vascular Events in HIV

This clinical trial is testing to see if Pitavastatin can prevent heart disease in people with HIV infection who are taking HIV medications. The study is a prospective, double-blind, randomized, placebo-controlled, multicenter phase IV efficacy study.  Participants are randomly assigned to either Pitavastatin or placebo.  Pitavastatin has been approved by the FDA for a different use, to decrease cholesterol.

You may be eligible for REPRIEVE if you:

  • Have HIV and are between the ages of 40 and 75
  • Have been on antiretroviral therapy (ART) for at least 6 months
  • Have no history of cardiovascular disease
  • Are not currently taking a statin drug.

UIC Principal Investigator: Richard M. Novak MD

Study Coordinator: Regina Harden

For more information:

If you are interested in this study – please contact Project WISH to arrange for a phone screen at 312-413-5897


We offer three flu season studies, including a clinical trial of a treatment drug, and observational studies of influenza. If you are a UIH provider and have a patient who currently has flu-like symptoms or confirmed influenza, please call Project WISH at 312-413-5897.

UIC Principal Investigator: Richard M. Novak M.D

Study Coordinator: Marla Schwarber, RN

INSTRUCTIONS: In order to add a sidebar anchor:

  1. Duplicate the existing item, listed as a 1/6 text field. (Or create a 1/6 column and add a text field, modify the class so it’s exactly “additionalAnchor”).
  2. Modify the text field inside the 1/6 column. Inside there, modify the HYPERLINK so that it would go to a corresponding section with a “#” in front of it. (Example, we have a “chief” section on the page, then it would make sense to have the hyperlink go to “#chief”)
  3. Then change the hyperlink TEXT to a appropriate label.
  4. IMPORTANT: If not done already, go into that CONTAINER that corresponds to your anchor (i.e. Meet The Chiefs), and add an ID matching the anchor’s HYPERLINK WITHOUT the “#”, i.e. “chief”.
  5. (If using side bar widget box, then there’s a saved copy of a widget box COLUMN, grab it in the column library, it should 1/6 of a length of a column.)

NOTE: Order added to the sidebar is from last to first.