Congratulations to Anand Srivastava, MD, MPH who received the 2023 Carl Gottschalk Research Scholar Grant for his project: Functional MRI for Enhanced Phenotyping of CKD.
Dr. Srivastava’s patient centered-research focuses on discovery and validation of novel non-invasive biochemical and imaging biomarkers that will identify high-risk patients with kidney diseases to optimize conduct of clinical trials and serve as tools for drug development.
His team will obtain kidney functional magnetic resonance imaging (fMRI)-derived assessments of fibrosis, oxygen status, and perfusion on participants with CKD undergoing a research native kidney biopsy enrolled at two Recruitments Sites of the Kidney Precision Medicine Project. They will test the reproducibility of kidney fMRI across multiple sites and the associations of kidney fMRI-derived biomarkers with chronic histopathologic lesions in patients with CKD. The hope is that this line of investigation will lead to further development of novel imaging tools to provide non-invasive assessments of critical histopathologic lesions that have prognostic value. Further development of novel non-invasive imaging may also allow for precision medicine approaches to identify sub-phenotypes of patients with CKD or serve as surrogate markers of chronic histopathologic lesions in future drug development trial.
See foundation’s announcement here: KidneyCure | Spotlights/Q&A – Who We Fund