A mother-daughter group randomized controlled trial to reduce sexually transmitted infections in Black/African-American adolescents

Geri Donenberg, PhD

CDIS Researchers published findings of a 2-arm randomized controlled trial exploring the efficacy of IMARA, a mother-daughter psychosocial STI/HIV prevention program for Black/African-Americans. The study explored the effect of the program on incidents of sexually transmitted infections (STIs) at 12-months when compared to a time-matched health promotion control program. Girls who received IMARA were 43% less likely to contract a new STI in the 12-month post-intervention period compared with those in the health promotion control program. Findings provide early evidence for IMARA’s efficacy, such that IMARA protected against STIs at 12-months among adolescent Black/African-American girls.

Donenberg GR, Kendall AD, Emerson E, Fletcher FE, Bray BC, McCabe K. IMARA: A mother-daughter group randomized controlled trial to reduce sexually transmitted infections in Black/African-American adolescents. PLoS One. 2020 Nov 2;15(11):e0239650. doi: 10.1371/journal.pone.0239650. PMID: 33137103; PMCID: PMC7605636.