BMS 646  Cell and Tissue Biology:  4 Credit Hours

Placement in the Curriculum:  Year One
Duration:   August - April

Synopsis:    In Cell & Tissue Biology students learn about the structures and function of cells and tissues in organs of the human body and learn about clinical correlations of cell and tissue functions.  The course covers cell biology; the cell and tissue biology of basic epithelial, connective, muscle, and nervous tissues; and the cell and tissue biology of  blood, skeletal, hepato-pancreatic, lymphoid, cardiovascular, respiratory, digestive, endocrine, urinary, reproductive, integumentary and special sense systems.  The Cell &  Tissue Biology Course integrates material from the nanoscopic domains of molecular biology, biochemistry, and physiology with the macroscopic domains of gross anatomy and the patient.

   In the process of completing this course, students acquire the following competencies:
●    Knowledge of the structural components of cells.
●    Understanding of the structure of cells in relation to chemical and physiological processes.
●    Knowledge of the basic tissues and cells which make up human central organs, distributed organs, and organ systems.
●    Understanding of the role of basic tissues and cells in organ function.
●    Knowledge of clinical correlations of cell and tissue function in human organs and organ systems.
●    General skills in the assessment of visual data.
●    Specific skills in the interpretation of images of cells and tissues.
●    Assimilation of basic medical science terminology and technology.
●    Practical use of the light microscope.
Key Words:    Cell structure and function, epithelium, connective tissue, muscle, nerve tissue, heart and blood vessels, cartilage and bone, blood and hemopoiesis, lymphocytes and  macrophages, lymphoid tissue and organs, lung and respiratory tract, salivary glands, esophagus, stomach, small and large intestine, liver, gall bladder, pancreas, pituitary gland, adrenal glands, thyroid, parathyroid, kidney and urinary tract, testes and male reproductive tract, ovary and female reproductive organs, placenta, mammary gland, skin, eye, ear.

Assessment:    Three in-term exams and a comprehensive end of term (April) final exam.
The exams assess students’ knowledge of cell and tissue structure in relation to function and clinical correlations, as presented in the text, and in lecture and laboratory sessions.  Competency sought is at the level of the text and lecture.  Exam questions are multiple choice.  The majority of in-term exam questions are based on viewing of cell and tissue structures in the light microscope or viewing of light micrographs and electron micrographs.  Questions based on viewing of structures are a minor component of the Final exam.
James Scholar students demonstrate competencies by sitting for exams in the context of the Cell & Tissue Biology Course for regular medical students.

Instructional Features: 
   Plenary lectures and handouts; breakout microscopy laboratory sections; comprehensive student histological slide loan collection.
Faculty laboratory instruction and student microscopy of histological slide preparations; specialized demonstration slides; laboratory manual constructed by Department of Anatomy and Cell Biology faculty. Demonstration exams prepared by Department of Anatomy and Cell Biology faculty; introduction to the use of interactive Histology learning programs available on computers in the medical student center; Tissue Biology website. Interactive small group faculty-student review and discussion sessions; full faculty access through “walk-in” office opportunities and/or scheduled appointment hours.