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H Engelhard, MD, PhD

Herbert H. Engelhard, MD, PhD

Associate Professor
Chief of Neuro-Oncology Section


Email: hengel@uic.edu

 

Experience

Fellowship:
Brain Tumor Research Fellow
Children's Memorial Hospital
Northwestern University
Chicago, Illinois

Residency:
Northwestern Memorial, Children's
Memorial and VA Lakeside Hospitals
Northwestern University
Chicago, Illinois (Neurosurgery)

Education

Medical School:
M.D., Duke University
Durham, North Carolina

Graduate School:
Ph.D., Tumor Cell Biology
Northwestern University Chicago, Illinois

Undergraduate:
With Distinction; Magna Cum Laude
Duke University Durham, North Carolina

Certification

Board Certified:
American Board of Neurological Surgery

Medical Licensure:
Illinois

Appointments

Clinical:

  • Director, UIC Neuro-Oncology Program
    University of Illinois at Chicago
  • Chief, Section of Neuro-Oncology,
    Department of Neurosurgery, University of Illinois at Chicago

Hospital:

  • University of Illinois at Chicago Medical Center
  • Vista Medical Center
  • Midwestern Regional Medical Center
  • Alexian Brothers Medical Center

Clinical Interests

  • Tumor: malignant and benign
  • Hydrocephalus
  • Spinal disorders


Research Interests

  • Innovative brain tumor therapies such as interstitial chemotherapy, differentiation therapy/apoptosis, gene therapy, immunotherapy, direct brain infusion, combination therapies, molecular biology of brain tumors; tumor markers, phenotypic assays, molecular mechanisms, differential gene expressions/microarrays.


Awards/Achievements

  • Continuing Education Award in Neurosurgery
  • Physician's Recognition Award for Continuing Medical Education
  • Research Society of Neurological Surgeons
  • Fellowship, American College of Surgeons
  • Commission on Cancer, American College of Surgeons


Selected Publications

"Convection-Enhanced Delivery of a Histone Deacetylase Inhibitor Delays Progression of Malignant Gliomas In Vivo"

"Clinical Presentation, histology and treatment of 431 patients with primary tumors of the spinal cord, spinal meninges and cauda equina"

"Up-regulation of the Tumor Suppressor p27 (Kip1) in Human Glioma Cells"

Engelhard HH, Stelea A, Mundt A: Oligodendroglioma: Clinical features, treatment and prognosis. Surgical Neurology 60 (5): 443-456, 2003.

Jho DH, Engelhard HH, Gandhi R, Chao J, Babcock T, Ong E, Espat NJ: Ciliary neurotrophic factor upregulates ubiquitin-proteasome components in a rat model of neuronal injury. Cytokine 27 (6): 142-151, 2004

Guzman G, Oh S, Shukla D, Engelhard HH, Valyi-Nagy T: Expression of entry receptor nectin-1 of herpes simplex virus 1 and/or herpes simplex virus 2 in normal and neoplastic human nervous system tissues. Acta virologica 50 (1): 59-66, 2006.

Barshes N, Demopoulos A, Engelhard HH: Anatomy and physiology of the leptomeninges and CSF space. In Abrey LE, Chamberlain MC, Engelhard HH (eds.) Leptomeningeal Metastases. New York: Springer, 2005, pp. 1-16

Engelhard HH, Corsten L: Leptomeningeal metastasis of primary central nervous system (CNS) tumors. In Abrey LE, Chamberlain MC, Engelhard HH (eds.) Leptomeningeal Metastases. New York: Springer, 2005, pp. 71-86

Engelhard HH, Valyi-Nagy T: Biology of the blood-brain and "blood-brain tumor" barriers. In Newton H (ed.) Handbook of Brain Tumor Chemotherapy. San Diego: Elsevier Publishers, 2005.