Research Report: May 2009

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Publications

Hughes JR. Reply to Sudden unexpected death in epilepsy. It's important to know that it is cold outside. Epilepsy Behav;2009;14:708.

Hughes JR. Presence of thimerosal in vaccines. Epilepsy Behav 2009;14:710.

Hughes JR. Commentary on "Some correlations between the electroencephalogram and normal and pathologic mental processes by H. Landolt”. Epilepsy Behav 2009;14:452-453.

Hughes JR. A review of sudden unexpected death in epilepsy: prediction of patients at risk. Epilepsy Behav 2009;14: 280-287.

Meriggioli MN, Sanders DB. Myasthenia gravis: emerging clinical and biological heterogeneity. Lancet Neurol 2009;8:475-490.

Meyers PM, Schumacher HC, Higashida RT, Barnwell SL, Creager MA, Gupta R, McDougall CG, Pandey DK, Sacks D, Wechsler LR, American Heart Association. Indications for the performance of intracranial endovascular neurointerventional procedures: a scientific statement from the American Heart Association Council on Cardiovascular Radiology and Intervention, Stroke Council, Council on Cardiovascular Surgery and Anesthesia, Interdisciplinary Council on Peripheral Vascular Disease, and Interdisciplinary Council on Quality of Care and Outcomes Research. Circulation 2009;119:2235-2249.

Vaillancourt DE, Spraker MB, Prodoehl J, Abraham I, Corcos DM, Comella CL, Little DM. High-resolution diffusion tensor imaging in the caudal portion of the substantia nigra of de novo Parkinson’s disease. Neurology 2009;72:1378-1384.

Zakarija A, Kwaan HC, Moake JL, Bandarenko N, Pandey DK, McKoy JM, Yarnold PR, Raisch DW, Winters JL, Raife TJ, Cursio JF, Luu TH, Richey EA, Fisher MJ, Ortel TL, Tallman MS, Zheng XL, Matsumoto M, Fujimura Y, Bennett CL. Ticlopidine- and clopidogrel-associated thrombotic thrombocytopenic purpura (TTP): review of clinical, laboratory, epidemiological, and pharmacovigilance findings (1989–2008). Kidney International 2009;75(Suppl 112):S20–S24.

Conference Presentations

Jacobs R, Little DM, Palmer A, Schenkel L, Pavuluri M (February 2009). Impact of emotion on language processing in pediatric bipolar disorder. International Neuropsychological Society, Atlanta, GA.

Kapur R, Navare S, Little D, Bhatt H, Blair NP, Lim JI (May 2009). Comparison of adult open globe injuries and outcomes in an inner city population: 1998-2003 compared with 2004-2008. Presented at the annual meeting of the Association for Research in Vision and Ophthalmology, Miami FL.

Ruland S (May 2009). Target organ damage: stroke. Presented at the annual meeting of the The American Hypertension Society's 24th Annual Scientific Meeting, San Francisco, CA.

Book Chapters

DeBaun MR, Gorelick PB, Som S. Strategies for Recruiting and Retaining Minorities. In K. Woodbury-Harris & Bruce Coull (Eds.): Clinical Trials in the Neurosciences, 2009. New York: Karger.

Testai FD, Gorelick PB. Stroke in black patients. In: Goldstein LB (Ed.): Primer on Stroke Prevention and Treatment: An Overview Based on AHA/ASA Guidelines. New York, USA: John Wiley and Sons, 2009: pp. 129-141.

Legislation Authored

The National Pediatric Acquired Brain Injury Plan
M Barr, JE. Baumgartner, G Bedell, R Pardes-Berger, PM Berger-Gross, B Eagan-Brown, S Bond Chapman, LG Cook, CS Cox, D Davis, R DePompei, J Dickens, JE Dise-Lewis, PB Donohue, D Gibbs, JMR Gillett, GA Gioia, CC Giza, A Glang, WA Gordon, S Grandinette, P Haldeman, G Hotz, JV Hunter, L Hyman, J Kuluz, S Ladak, M Lash, K Lawson, H Levin, DM Little, M Lutz, JE Max, G McMillan, M Mikol, P Molloy, DP Mooney, PD Patrick, A Pitt, E Pracht, MR Proctor, RC Savage, H Shane, E Simpser, DG Stein, HG Taylor, JJ Tepas, BJ Todis, L Turkstra, JS Tyler, MS Vavilala, SL Wade, MS Wainwright, S Weinstein, DJ Winchester, KO Yeates, M Ylvisaker.

Other events

Grants Submitted

Investigator: H Lipton (PI)
Title: Theiler’s virus as a potential cause of Vilyuisk encephalitis.
Sponsor: NIH R21 NS 062304-01.

Investigators: Deborah Little (PI); Co-I: Marilyn Kraus, John Sweeney, Neil Pliskin, X. Joe Zhou
Title: Thalamic DTI as a Biomarker for Traumatic Brain Injury
Sponsor: NIH
Total Direct Cost: $998,100

Investigators: Deborah Little (PI); Site PIs: Carol MacMillan, Mark Wainwright, Steven Gillenwater Title: Pediatric Brain Injury Model System (Lead site, Regional site, Level I Center).
Institutions: University of Illinois Medical Center, University of Chicago, Northwestern University, Rush University
Sponsor: NA; under review for direct congressional funding
Project Period: 6/1/10 – 5/31/20
Direct Costs/Year: $11,765,000

Investigator: Meriggioli M (PI)
Title: Immunoregulation of experimental autoimmune myasthenia gravis
Sponsor: NIH/NINDS Recovery Act Funds for Administrative Supplements

Investigators: Pandey D (PI); Co-I: Aiyagari, V.
Title: Social Determinants of Cardiovascular Health and Health Behaviors in South Asians
Sponsor: NIH Challenge Grant

Investigators: PI: Daniel Corcos, David Vaillancourt; Co-I: Deborah Little, X. Joe Zhou, Jeff Kordower, Christopher Goetz, Kathleen M. Shannon.
Title: Diffusion Tensor Imaging in Grey Matter: A Biomarker of Parkinson’s Disease
Sponsor: NIH Challenge Grant
Project Period: 9/1/2009 – 8/31/2011
Total Direct Cost: $999,990

Investigators: PI: Orly Lazarov; Co-I: Deborah Little, X. Joe Zhou, David Nyenhuis, Laura Pedelty
Title: Comparative Effectiveness of Brain Imaging and Blood Biomarkers in Alzheimer’s Disease
Sponsor: NIH Challenge Grant
Project Period: 9/1/2009 – 8/31/2011
Total Direct Cost: $999,000

Investigators: PI: Mani Pavuluri; Co-I: Deborah Little, John Sweeney, X. Joe Zhou
Title: Identification of Neural Circuits for pediatric bipolar and ADHD with fMRI and DTI.
Sponsor: NIH Challenge Grant
Project Period: 9/1/2009 – 8/31/2011
Total Direct Cost: $990,000

Investigators: Beatrice Edwards at NWU; Co-I: Pandey D.
Title: Novel Biomarkers for Fractures in Breast Cancer Survivors
Sponsor: NIH Challenge Grant

Investigators: PI: Beatrice Edwards at NWU; Co-PI: Pandey D.
Title: Osteoporotic Fractures in Breast Cancer: Incidence, Role for Bone Architecture and Genetics Sponsor: American Cancer Society

Investigators: PI: Charles Bennette at NWU; Co-PI: Pandey, D.
Title: Risk factors for JC virus reactivation among patients with rituximab exposure: A case-control study.
Sponsor: Genentech

Investigators: PIs: Thomas Prohaska and Susan Hughes; Co-I: Deborah Little
Title: Gerontological Public Health Training Program
Sponsor: NIH

Investigators: PIs: Simon Alford and Daniel Corcos; Co-I: Deborah Little
Title: Early PhD Training in the Neurosciences
Sponsor: NIH

Investigators: PI: Mark Rasenick; Co-I: Deborah Little
Title: Training in the Neuroscience of Mental Health
Sponsor: NIH

Investigators: PI: Mark Rasenick; Co-I: Deborah Little
Title: Training in the Clinical Neurosciences
Sponsor: Howard Hughes Medical Institute