Research Report: June 2009

Publications

Aiyagari V, Badruddin A. The management of hypertension in acute stroke. Expert Review of Cardiovascular Therapy 2009;7:637-646.

Aiyagari V. Correction of coagulopathy secondary to oral and parenteral anticoagulants. Continuum Lifelong Learning Neurol 2009;15:130-157.

Aiyagari V, Gorelick PB. Management of blood pressure for acute stroke and recurrent stroke prevention. Stroke 2009; 40:2251-6.

Fan J, Son, K.-N., Arslan S.Y, Liang Z, Lipton, HL. (2009) The Theiler’s murine encephalomyelitis virus leader protein is the only nonstructural protein tested that induces apoptosis when transfected into mammalian cells. J Virol. 83:6546-6553.

Gorelick PB. Transient Ischemic Attack: New Definition, Importance of Emergent Diagnosis, and Treatment Guidelines. The Journal of Medicine March/April 2009; 2: 3-10.

Gorelick PB. Cerebral microbleeds [editorial]. Evidence of heightened risk associated with aspirin use. Arch Neurol 2009;66:691-693.

Invited Presentations

Gorelick PB (June 2009). Vascular cognitive impairment: new insights. American Heart Association / American Stroke Association delegate and invited stroke symposium speaker at the Tiantan International Stroke Conference, Beijing, China.

Other events

Patents Awarded

Number: United States Patent # 7,527,972B2
Title: Uses of Bispecific Antibody Coated Dendritic Cells Pulsed With Antigen and GM-CSF in Immune Regulation.
Investigators: Prabhakar BS, Holterman MJ, Vasu C, Meriggioli MN.
Award Date: May 5, 2009.

Grants Submitted

Investigators: PI: Deborah Little; Co-Is: John Sweeney, Molly Gilbert, Marilyn Kraus, CPT Michael Dretsch, Elizabeth Geary, Neil Pliskin, James Young, Konstantin Slavin, Marylou Tomyanovich, Vijaya Patil, Rita Shapiro.
Title: Sensitivity and Specificity of Oculomotor Function for TBI Diagnosis
Sponsor: VA
Total Direct Cost: $747,760

Investigators: PI: Deborah Little; Co-Is: Marilyn Kraus, CPT Michael Dretsch, Elizabeth Geary, Neil Pliskin, X.Joe Zhou, Marylou Tomyanovich, Vijaya Patil, Rita Shapiro.
Title: Effects of Injury Mechanism on Cerebral White Matter Burden in Mild TBI
Sponsor: VA
Total Direct Cost: $743,015

Investigators: PI: D Nyenhuis; Co-Is: P. Gorelick, X. Joe Zhou, L. Pedelty, G. Stebbins
Title: Validation of the NINDS VCI Neuropsychological Protocols in Three Patient Groups
Sponsor: NIH/NINDS
Total Direct Cost: $1,988,645

Investigators: PIs: Janet Szlyk & Deborah Little
Title: Measuring Brain Network Changes in Response to Vision Rehabilitation
Sponsor: VA
Total Direct Cost: $682,122

Grants Awarded

Investigator: H. Lipton
Title: R21 NS062304. Theiler’s virus as a potential cause of Vilyuisk encephalitis.
Sponsor: NIH