Welcome to the Yuan Lab! We are a research lab focused on vascular biology, electrophysiology, and the pathogenic mechanisms of pulmonary vascular disease. We use the combined techniques of patch clamping, digital imaging fluorescence microscopy, and cellular and molecular biology techniques to investigate the roles of ion channels and intracellular Ca2+ signaling in regulating vasomotor tone, and pulmonary vascular smooth muscle proliferation and apoptosis in order to understand the molecular mechanisms of idiopathic and thromboembolic pulmonary hypertension. The aim of our investigation is to identify new therapeutic targets and treatment strategies for pulmonary hypertension. A more thorough summary of the current projects in the lab is provided in the Research Focus.
Jason X.-Yuan, MD, PhD
Professor of Medicine and Pharmacology
Vice Chair for Scholarly Activities, Department of Medicine
Director, Program in Pulmonary Vascular Disease & Right Heart Function, UIC Center for Cardiovascular Research
Thanks for visiting!
The Yuan Lab