Nephrology


RESEARCH


 

Opportunities exist for trainees to be involved in ongoing research as well as with smaller and short term projects in both basic science and patient-oriented disciplines. Basic science research opportunities are available in different investigators' laboratories addressing a variety of interests related to cell biology, acute renal failure, autoimmunity, and acid-base physiology and pathophysiology.Nephology
  
Active clinical research protocols include the NIH sponsored Chronic Renal Insufficiency Cohort (CRIC) Study, the Hispanic Chronic Renal Insufficiency Cohort (H-CRIC) Study,  and the African American Study of Kidney Disease and Hypertension (AASK) Cohort Study. In addition, several protocols involving anemia and osteodystrophy management are being conducted in end stage renal disease patients.  Along with these projects, an opportunity for concomitant didactic work at the UIC School of Public Health is also available, including a program leading to a master degree in public health.  An ongoing affiliation with the Center for Management of Complex Chronic Care at the Jesse Brown VA Medical Center affords further opportunities in health services research targeted at chronic and end-stage kidney disease.


Research Studies


Chronic Renal Insufficiency Cohort (CRIC) Study

This study was established in 2001 by the National Institute of Diabetes, Digestive, and Kidney Diseases (NIDDK) to improve the understanding of chronic kidney disease (CKD) and related cardiovascular illness. The major goals of this multicenter cohort study are to investigate the risk factors for progression of renal disease and cardiovascular disease in patients with mild to moderate chronic kidney disease.

PI: James Lash, MD


Hispanic Chronic Renal Insufficiency Cohort Study

The major goals of this NIDDK-sponsored cohort study are to investigate risk factors for progression of renal disease and cardiovascular disease in Hispanics with chronic kidney disease.
PI: James Lash, MD


Health Disparities in Chronic Kidney Disease Mentoring Program

This K24 Midcareer Investigator Award in Patient-Oriented Research provides support for mentoring new clinician investigators to study health disparities in chronic kidney disease.
PI: James Lash, MD


Mexican Chronic Renal Insufficiency Cohort Study

The overall objective of this Fogarty International Research Collaboration Award is to recruit and retain a cohort of Mexicans with mild-to-moderate CKD at the Instituto Nacional de Cardiología Ignacio Chávez in Mexico City with the long-term goal of understanding the epidemiology of kidney disease in Mexicans.
PI: James Lash, MD


Systolic Blood Pressure Intervention Trial (SPRINT)

The major goal of this National Heart, Lung, and Blood Institute-sponsored multicenter, randomized clinical trial is to determine whether treating systolic blood pressure to a lower goal than currently recommended, will reduce cardiovascular disease.
PI: James Lash, MD


Health Literacy in Hispanics with Chronic Kidney Disease

The goal of this K23 Career Development Award is to examine the association between health literacy and the progression of kidney disease and to develop a low-literacy culturally sensitive touch table application to improve knowledge of hypertension in Hispanics with chronic kidney disease.
PI: Claudia M. Lora, MD, MS


Gender Disparities and Vascular Function in Chronic Kidney Disease Outcomes

This goal of this K23 award is to investigate gender-related disparities in chronic kidney disease progression and cardiovascular outcomes.
PI: Ana C. Ricardo, MD, MPH


Increasing Adoption of Home Dialysis in VA

The purpose of this study is to develop and evaluate tools to increase use of home dialysis in Veterans.
PI: Michael J. Fischer, MD, MSPH


Bringing Care to Patients: A Patient Centered Medical Home for Kidney Disease

The goal of this Patient-Centered Outcome s Research Institute is to study the impact of a patient-centered medical home model on outcomes in patients with end-stage renal disease.
PI: Denise Hynes, PhD, MPH, RN