gastro


RESEARCH

 

lab pic 1lab pic 2lab pic 3lab pic 4

 

Research in GI/Hepatology division

 

The broad focus of our research is to better understand digestive diseases for the development of new therapeutic approaches.  Investigators in the division engage in a spectrum of research comprising pre-clinical, translational and clinical studies in gastrointestinal systems including pancreas, small intestine, colon and liver.  Included under this umbrella are understanding ion transport mechanisms in infection and inflammatory diarrhea; amelioration of inflammation through probiotics in inflammatory bowel diseases (IBD); identifying novel pathways to regulate bile acid and cholesterol absorption for the treatment of hypercholesterolemia; understanding the role of serotonin transporter and serotonergic machinery in gut disorders; understanding dysregulation of growth signaling pathways in inflammation, colon and pancreatic cancers; understanding the role of microbiome in the development of diarrheal disorders, gut inflammation and colorectal cancers; investigating the impact of decreased vitamin D signaling in colon cancers. Research is also focused on understanding how gut-liver axis plays an important role in development and progression of gut inflammation, metabolic disorders and experimental NASH. In addition, we have initiated several disease registries to facilitate clinical research. Meet Our Faculty and Know Their Expertise

 

Major Areas of Research

Epithelial Transport & Diarrheal Disorders

Cancer Research

Host-Pathogen Interactions & Gut Microbiota

Inflammation

Nutrition & Metabolism


Learn More About Our Research 

Epithelial Transport Group

 


Alrefai Waddah A


Bile Acid Transport, Cholesterol Transport

Borthakur Alip

 

Electrolyte and Short Chain Fatty Acid Transport

Dudeja Pradeep K

 

Na+, Cl- and Monocarboxylate Transporters

Gill Ravinder K

 

Serotonin Transporter, Cl- Transport

Saksena Seema

 

MDR1, Cl- Transport, Na+/H+ Exchangers

Cancer Research Group

 

Boulay Brian


Polyps of the  GI Tract

Carroll Robert

 

Colon Cancer

Gartel Andrei

 

Hepatocellular Carcinoma

Grippo Paul

 

Pancreatic Cancer

Jung Barbara

 

Colon cancer

Kahn Lyn Sue

 

Cancer of the GI Tract

Sun Jun

 

Colon and Breast Cancer

Gut Microbes Group

 

Alrefai Waddah A


Enteropathgenic E. coli (EPEC), Probiotics

Borthakur Alip

 

Probiotics, EPEC, Gut Microbiome 

Dudeja Pradeep K 

 

Gut Microbiome, Probiotics, EPEC, C. difficile, CTX 

Gill Ravinder K

 

EPEC, AIEC, Probiotics, Gut microbiota and serotonin

Jung Barbara

 

Gut Microbiome in Colon Cancer

Koppe Sean

 

Viral Hepatitis

Naveed Ammara

 

Viral Hepatitis

Saksena Seema

 

Probiotics, EPEC

Sun Jun

 

Salmonella, Gut microbiome

Intestinal Inflammation Group

 

Alrefai Waddah A


IBD, Gut-Liver Axis

Borthakur Alip

 

IBD

Dudeja Pradeep K 

 

IBD, C. rodentium & TNBS induced colitis, C. difficile

Gill Ravinder K

 

Ileal Inflammation, Colitis, AIEC

Nannegari Veena

 

IBD Patients

Saksena Seema

 

IBD, Experimental colitis

Sun Jun

 

Salmonella

Nutrition & Metabolism

 

Alrefai Waddah A
Diabetes, Gut-Liver Axis
Berger-Fleishman Reed
  Obesity, Bariatric Surgery
Dudeja Pradeep K

Nutrient Sensing, FOXO1 and Insulin Resistance

Research



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