Victoria S. Lee, MD

Assistant Professor, Rhinology, Sinus & Skull Base Surgery

Victoria S. Lee, MD

Office Locations:

Eye and Ear Infirmary (EEI)
1855 W. Taylor Street
Chicago, Illinois 60612
Appointments: 312.996.6553
Fax: 312.996.4910

Magnificent Mile
60 East Delaware Place
Suite 1422
Chicago, Illinois 60611
Appointments: 312.255.8812
Fax: 312.255.8904


Dr. Lee is a specialist in sinus and skull base surgery and part of the rhinology division with Dr. Stephanie Joe. She completed her subspecialty training in sinus and skull base surgery at the Johns Hopkins Hospital and her otolaryngology residency at the University of Washington. She earned her medical degree from Northwestern University. She is board-certified in Otolaryngology – Head and Neck Surgery. She was born and raised in Wisconsin and was excited to return to the Midwest after the completion of her medical training.

As a specialist in sinonasal disease, her areas of expertise include nasal obstruction, allergy, sinusitis, nasal polyps, and sinonasal tumors. She is experienced with the latest technological advances in the field and specializes in minimally invasive endoscopic approaches to treat sinonasal as well as skull base and orbital pathology, including pituitary and other tumors, cerebrospinal fluid leaks, blocked tear ducts, and thyroid eye disease. More..

She is actively involved in rhinologic clinical outcomes research. During her training, she co-authored more than 15 peer-reviewed publications and received both national societal and industry grant funding as well as several awards for her research. She is dedicated to continually translating this new knowledge to clinical practice.

Dr. Lee strives to achieve a patient-centered and multidisciplinary approach to her medical and surgical care. She will work tirelessly to get to the bottom of any problem her patients may have, no matter how complicated. Show Less..

Specialties & Services
  • Allergy - Nasal Allergy
  • Cerebrospinal Fluid Leaks
  • Chronic Sinusitis
  • Ear, Nose, and Throat
  • Endoscopic Orbital Decompression / Thyroid Eye Disease
  • Functional Endoscopic Sinus Surgery / Balloon Sinuplasty
  • Head and Neck Cancer Surgery
  • Minimally Invasive Treatment of Sinus / Nasal Conditions
  • Nasal Obstruction
  • Nasal Polyps
  • Nasal Surgery
  • Otolaryngology
  • Rhinology
  • Sinus Disease
  • Sinus Surgery
  • Sinus / Nasal Tumors
  • Skull Base Surgery
  • Skull Base Tumors / Pituitary Tumors
  • Smell Loss
Show Less..
Board Certification:American Board of Otolaryngology
Residency: University of Washington School of Medicine, Otolaryngology – Head and Neck Surgery
Fellowship:Johns Hopkins University School of Medicine, Rhinology and Skull Base Surgery
Fellowship:University of Washington School of Medicine, Clinical Research (T32), Department of Otolaryngology – Head and Neck Surgery
Medical School: Northwestern University Feinberg School of Medicine
Professional Associations
  • Member, American Academy of Otolaryngology-Head and Neck Surgery
  • Member, American Rhinologic Society
  • Member, Triological Society
  • Reviewer, International Forum of Allergy & Rhinology
  • Reviewer, American Journal of Rhinology & Allergy

Research Focus

Topical therapies in the treatment of recalcitrant chronic rhinosinusitis

  • In patients who have persistent sinus disease despite standard medical and surgical interventions, better defining indications for topical therapies. What factors may predict success in this setting?
  • Explore different modes of delivery and compounding for topical therapies.
  • Assess the effectiveness of topical alternative therapies on a variety of outcome measures, including symptoms/quality-of-life, microbiological eradication, and endoscopic appearance.
  • Evaluate for side effects and tolerance associated with topical therapies.

Current Projects

  • Manuka honey sinus irrigation in the treatment of cystic fibrosis-related chronic rhinosinusitis
  • Topical probiotics in the treatment of recalcitrant chronic rhinosinusitis
  • Topical and systemic pharmacologic inhibition of c-Jun N-terminal kinase to protect olfactory neurons in chronic sinusitis-type inflammation


  • Lee VS. Rhinosinusitis: Topical irrigations for chronic rhinosinusitis. Immunol Allergy Clin North Am. Accepted for publication.
  • Lee VS, Lin SL. Updates in Pediatric Otolaryngology: Allergy and the Pediatric Otolaryngologist. Otolaryngol Clin N Am. 2019;52(5):863-873.
  • Lee VS, Humphreys IM, Purcell PL, Davis GE. Manuka honey sinus irrigation for the treatment of chronic rhinosinusitis: a randomized controlled trial. Int Forum Allergy Rhinol. 2017;7(4):365-372.
  • Lee VS, Davis GE. Culture-directed topical antibiotic treatment for chronic rhinosinusitis. Am J Rhinol Allergy. 2016;30(6):414-417.
  • 2nd Place Clinical Paper, Rhinoworld Chicago, 2019
  • 1st Place Poster Presentation, American Rhinologic Society Annual Meeting, 2017
  • Centralized Otolaryngology Research Efforts (CORE) Research Award, 2015