Dr. Fernando Testai is an Assistant Professor in Neurology.
Dr Testai earned his degree in biochemistry from the Faculty of Pharmacy and Biochemistry and his medical degree from the Faculty of Medicine of the University of Buenos Aires. He did his doctoral thesis in the area of neurochemistry and obtained his PhD in the year 2000. He completed a post-doc in the area of apoptosis at the University of Chicago and did his Residency in neurology at the University of Chicago where he served as chief resident. Dr Testai completed his fellowship in vascular neurology at the University of Illinois at Chicago under the supervision of Dr Ruland and Dr Gorelick in 2008.
Dr. Fernando Testai's focus is on evaluation and treatment of patients with acute stroke, and his areas of interest are large-artery intracranial occlusive disease, intracerebral hemorrhage, and stroke secondary to metabolic disease.
Acute Hemorrhagic Stroke. Pathophysiology and Medical Interventions: Blood Pressure Control, Management of Anticoagulant-Associated Brain Hemorrhage and General Management Principles (2008) FD Testai and V Aiyagari. Neurology Clinics. In press.
"Special Topics Chapter: Stroke in Blacks". FD Testai and PB Gorelick. American Stroke Association/American Hear Association guidelines and Statements Handbook. LB Goldstein ed. In press.
Surgical versus endovascular treatment subarachnoid hemorrhage (2008) (in Spanish) Testai FD and Goldenberg FD. Intensive Medicine (Journal of the Argentinean Society of Intensive Care). In press.
Differential regulation of sphingomyelin synthesis and catabolism in oligodendrocytes and neurons (2008) Kilkus J, Goswami R, Dawson SA, Testai FD, Beredyshev E, Han X, and Dawson G. J Neurochem, 106:1745-57.
Acid Sphingomyelinase and inhibition by phosphate ion: role of inhibition by PtdIns (3,4,5)P3 in oligodendrocytes cell signaling (2004), Testai FD, Landek MA, Goswami R, Ahmed M, Dawson G. J Neurochem, 89:634-644
Regulation of sphingomyelinases in cells of the oligodendrocyte lineage (2004), Testai FD, Landek MA, Dawson G. J Neuros Res, 75:66-74
Ceramide in Rafts (detergent-insoluble fraction) mediates cell death in neurotumor cell lines (2003), Kilkus J, Goswami R, Testai FD, Dawson G. J Neuros Res, 72:65-75
Conotoxin MI inhibits the alpha-delta acetylcholine binding site of the Torpedo marmorata receptor (2002), Cortez LM, Del Canto SG, Testai FD, Biscoglio MJ. Biochem Biophys Res Commun, 295:791-795
Histidine 186 of the nicotinic acetylcholine receptor alpha subunit requires the presence of the 192-193 disulfide bridge to interact with alpha-bungarotoxin (2000), Testai FD, Venera GD, Peña P, Biscoglio MJ. Neurochem Int, 36:27-33
Involvement of histidine 134 in the binding of alpha-bungarotoxin to the nicotinic acetylcholine receptor (1997), Venera GD, Testai FD, Peña C, Lacorazza HD, Biscoglio MJ. Neurochem Int, 31:151-157