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Gastrointestinal and Colon Clinical Trials

 

Study Name:

A Phase III Randomized Trial of Chemoembolization with or without Sorafenib in Unresectable Hepatocellular Carcinoma (HCC) in Patients with and without Vascular Invasion 

         

Purpose:

This randomized phase III trial is studying chemoembolization and sorafenib tosylate to see how well they work compared with chemoembolization alone in treating patients with liver cancer that cannot be removed by surgery.

Study Type: Treatment

Protocol: UIC 2010-1001 E1208

 

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A Phase III Trial of 6 Versus 12 Treatments of Adjuvant FOLFOX Plus Celecoxib or Placebo for Patients With Resected Stage III Colon Cancer.

         

Purpose:

This randomized phase III trial is studying giving oxaliplatin, leucovorin calcium, and fluorouracil together to compare how well they work when given together with or without celecoxib in treating patients with stage III colon cancer previously treated with surgery.

Study Type: Treatment

Protocol: UIC CALGB/SWOG 80702

 

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Study Name:

Phase III Randomized Study of Sorafenib (IND 69896, NSC 724772) Plus Doxorubicin versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma (HCC)

 

         

Purpose:

This randomized phase III trial is studying sorafenib tosylate and doxorubicin hydrochloride to see how well they work compared with sorafenib tosylate alone in treating patients with locally advanced or metastatic liver cancer. 

Study Type: Treatment

Protocol: UIC 2010-0811 CALGB 80802

 

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Study Name:

Randomized Phase III Trial of mFOLFOX7 or XELOX Plus Bevacizumab Versus 5-Fluorouracil/Leucovorin or Capecitabine Plus Bevacizumab as First-line Treatment in Elderly Patients With Metastatic Colorectal Cancer.

         

Purpose:

This randomized phase III clinical trial is studying how well combination chemotherapy plus bevacizumab with or without oxaliplatin works in treating older patients with metastatic colorectal cancer.

Study Type: Treatment

Protocol: NCCTG N0949

 

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Study Name:

Randomized Comparative Study Of Folfox6m Plus Sir-Spheres® Microspheres Versus Folfox6m Alone As First Line Treatment In Patients With Nonresectable Liver Metastases From Primary Colorectal Carcinoma.

         

Purpose:

This study is a randomized multi-center trial that will assess the effect of adding SIRT, using SIR-Spheres microspheres, to a standard chemotherapy regimen of FOLFOX as first line therapy in patients with non-resectable liver metastases from primary colorectal adenocarcinoma.

Study Type: Treatment

Protocol: UIC 2011-0435 STX 0206

 

 For study details, click here.

Internal users only: click here for protocol details and forms.

 

 

 

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